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tag brown fat developmental biology disease medicine

Treating Fat with Fat
Edyta Zielinska | May 1, 2012 | 7 min read
Is brown fat ready for therapeutic prime time?
Stem Cell Trial for Eye Disease Commences
Jef Akst | Sep 12, 2014 | 2 min read
Researchers at the RIKEN Center for Developmental Biology will treat the first patient in its clinical trial testing an induced pluripotent stem cell-based treatment for age-related macular degeneration.
Guts and Glory
Anna Azvolinsky | Apr 1, 2016 | 9 min read
An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.
Image of the tissue surrounding a pancreatic tumor thickening and scarring.
How Pancreas Injuries Can Cause Cancer in Mice
Dan Robitzski | Nov 9, 2021 | 4 min read
A key mutation turns healing cells into cancer promoters.
The Skinny Fat
Bruce Spiegelman | Jan 1, 2008 | 8 min read
The Skinny Fat FRANKLYN RODGERS / SCIENCE PHOTO LIBRARY All Fat Cell images courtesy of Patrick Seale What if you could make fat cells burn energy rather than store it? By Bruce Spiegelman Related Articles Energy-burning baby fat Two paths for a preadipocyte From an outsider's perspective, obesity seems like a simple problem to solve: Eat less, exercise more. But, the body regulates food intake and feelings of satiety as part of a tightly regulated home
Fat's Immune Sentinels
Justin Odegaard and Ajay Chawla | Dec 1, 2012 | 10 min read
Certain immune cells keep adipose tissue in check by helping to define normal and abnormal physiological states.
Flipping the Fat-Sensing Switch
Brendan Maher | Aug 18, 2002 | 6 min read
Image: Courtesy of David J. Mangelsdorf YIN AND YANG: Although they play opposite roles in bile acid production, these RXR heterodimers synergistically modulate cholesterol absorption and transport. When the molecular basis of Tangier disease was discovered in 1999,1 researchers lined up to study this orphan genetic disorder. Patients with Tangier have a propensity for heart disease and atherosclerosis, making this rare malady a model for some pressing health problems found in industrial
Week in Review: October 5–9
Tracy Vence | Oct 8, 2015 | 2 min read
This year’s Nobel Prizes; toward developing a brown fat-activating drug; certain antioxidants can increase the spread of melanoma in mice; anonymity and post-publication peer review
Lasker Awards Target Developmental, Diagnostic Genetics
Rebecca Andrews | Sep 29, 1991 | 6 min read
The Laskers are among the most prestigious medical research awards in the world and among the oldest in the United States. Since they were first presented in 1944, 49 winners have gone on to win Nobel Prizes. Jordan Gutterman of the M.D. Anderson Cancer Center in Houston, executive vice president of the Albert and Mary Lasker Foundation, and director of the awards program since earlier this year, attributes the prestige of the awards to their longevity and to the "extraordinary quality&quo
The Skinny on Fat Cells
Anna Azvolinsky | Nov 1, 2015 | 8 min read
Bruce Spiegelman has spent his career at the forefront of adipocyte differentiation and metabolism.

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