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Clostridium botulinum produces a transcription factor that can aggregate and self-propagate a prion-like form, leading to genome-wide changes in gene expression in E. coli, according to a study.

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A team of scientists was unable to replicate controversial, high-profile findings published in 2011.

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image: More Anti-CRISPR Proteins to Block Cas9

More Anti-CRISPR Proteins to Block Cas9

By | December 29, 2016

The latest CRISPR deactivators to be discovered turn off the Streptococcus pyogenes Cas9 widely used in genome editing.

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image: Keeping CRISPR in Check

Keeping CRISPR in Check

By | December 14, 2016

In bacteriophage genomes, researchers find three anti-CRISPR proteins that naturally inhibit CRISPR-Cas9 in one bacterial species and can do the same in human cells. 

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image: Video: Watch Cells Crawl To Firmer Ground

Video: Watch Cells Crawl To Firmer Ground

By | December 11, 2016

This collective migration, called durotaxis, depends on which cells get the best grip on a surface.

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Scientists present evidence of bacteria-driven mating in flagellate eukaryotes at the American Society for Cell Biology annual meeting.

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image: Phages Carry Antibiotic Resistance Genes

Phages Carry Antibiotic Resistance Genes

By | December 8, 2016

Researchers find evidence of antibiotic resistance genes in the DNA of viruses that infect bacteria.

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image: Controlled Splicing Extends Life Span in Roundworms

Controlled Splicing Extends Life Span in Roundworms

By | December 7, 2016

Increasing the expression of an RNA splicing factor mimics dietary restriction, prolonging life in nematodes. 

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image: “Celldance” Selections

“Celldance” Selections

By | December 5, 2016

Highlights from the American Society for Cell Biology’s 2016 video grant competition

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image: Famed Mammalian Embryologist Dies

Famed Mammalian Embryologist Dies

By | December 2, 2016

Andrzej Tarkowski’s research laid the groundwork for future advances in cloning, stem cell research, and in vitro fertilization.

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