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tag satellites genetics genomics

The Human Genome
Arielle Emmett | Jul 23, 2000 | 10+ min read
Life sciences took center stage virtually around the world June 26. President Bill Clinton, flanked on the left by Celera Genomics Group president J. Craig Venter and on the right by National Human Genome Research Institute director Francis S. Collins, announced the completion of "the first survey of the entire human genome."
Whole-Genome SNP Genotyping
Marilee Ogren | Jun 1, 2003 | 8 min read
Clockwise from top left: images courtesy of Affymetrix, Illumina, Sequenom and Illumina Take any two individuals, sequence and compare their genomic DNA, and you'll find that the vast majority (about 99.9%) of the sequences are identical. In the remaining 0.1% lie differences in disease susceptibility, environmental response, and drug metabolism. Researchers are understandably keen to dissect these variations, most of which take the form of single-nucleotide polymorphisms (SNPs). A SNP (pron
How Interconnected Is Life in the Ocean?
Catherine Offord | Nov 1, 2019 | 10+ min read
To help create better conservation and management plans, researchers are measuring how marine organisms move between habitats and populations.
Getting to Megabase
Jorge Cortese | Dec 5, 1999 | 7 min read
Large Fragment Cloning Products and Services Gone are the days when all you had to do to get out of grad school was identify and clone a new gene. Besides, with the information rapidly gathered through the Human Genome Project, there will soon no longer be a "new gene." Enormous projects such as sequencing entire genomes have created a need to play with bigger pieces of the puzzle, and a new universe of technologies adapted to large DNA fragments has appeared. Assignment of a new gene to a par
Sly Guys
The Scientist | Jul 1, 2014 | 10+ min read
Across the animal kingdom, dominance isn’t the only way for a male to score. Colluding, sneaking around, or cross-dressing can work, too.
Sons of Next Gen
Tia Ghose | Jun 1, 2012 | 8 min read
New innovations could bring tailored, fast, and cheap sequencing to the masses.
Methylation: Gene Expression at the Right Place and Right Time
Nadia Halim | Dec 5, 1999 | 7 min read
Courtesy of Richard Roberts, New England BiolabsModel methylation reaction: Cytosine nucleotide (red) is flipped out of the DNA double helix by a methyltransferase (white), so it can be methylated. The end product after the methyl group has been transferred to the DNA is pictured in green. A tenuous link between DNA methylation and development has existed for several years. Now findings substantiate the connection. Researchers have found the first human diseases caused by defects in the DNA meth
60 Members Elected to NAS
Barry Palevitz | Jun 25, 2000 | 6 min read
Editor's Note: On May 2, the National Academy of Sciences announced the election of 60 new members and 15 foreign associates from nine countries in recognition of their distinguished and continuing achievements in original research. Nearly half of the new members are life scientists. In this article, The Scientist presents photographs of some of the new members and comments from a few of them on their careers and on past and current research. A full directory of NAS members can be found online a
The Biggest Stories in Bioscience 2005
Ishani Ganguli | Dec 4, 2005 | 8 min read
Life scientists have been challenged more than ever this year not just to critically analyze data, but to better interpret those data for an increasingly critical public.
Iron Seeding Just Doesn't Pay
Sam Jaffe | Jul 4, 2004 | 6 min read
BRINGING ON THE NEXT ICE AGE?Dee Breger, Drexel UniversityAssumptions that tiny diatoms such as the ones shown above could fix carbon from the air and sink it to the bottom of the ocean have been hard to prove.The US Department of Energy has taken an interest in carbon sequestration, but a grand scheme to induce thick blooms of carbon-fixing algae has yet to bear fruit in early studies. The DOE directs a large share of its global warming budget to carbon-sequestration research, drawing on biolog

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