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image: DNA Replication Errors Contribute to Cancer Risk

DNA Replication Errors Contribute to Cancer Risk

By | March 23, 2017

A follow-up study confirms that random mutations acquired during normal stem cell division likely play a major role in cancer incidence.

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image: Low Mutation Rate in iPSCs

Low Mutation Rate in iPSCs

By | April 11, 2016

The mutation rate in induced pluripotent stem cells is 10 times lower than in somatic cells, scientists show.

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image: Estimating Epigenetic Mutation Rates

Estimating Epigenetic Mutation Rates

By | May 11, 2015

Generation-spanning maps of Arabidopsis thaliana DNA methylation allow researchers to compute how quickly epigenetic marks appear and disappear in the plant’s genome.

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image: Ebola Mutation Rate Quibble

Ebola Mutation Rate Quibble

By | March 27, 2015

A study suggests that the virus may not be evolving as quickly as a previous group estimated.

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image: Stem Cell Divisions Help Explain Cancer Risk

Stem Cell Divisions Help Explain Cancer Risk

By | January 1, 2015

An analysis of 31 tissues finds that random mutations acquired during stem cell divisions correlate with lifetime cancer risk.  

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image: Identifying Spurious Cancer Mutations

Identifying Spurious Cancer Mutations

By | June 19, 2013

Researchers reveal why analyses of cancer-causing mutations are riddled with false positives and demonstrate a new approach that eliminates the problem.

2 Comments

image: Ginormous Genome

Ginormous Genome

By | May 1, 2012

Researchers find organisms with huge genomes with high mutation rates, overturning a common expectation in evolutionary biology.

8 Comments

image: Our Missing Genes

Our Missing Genes

By | February 17, 2012

New research suggests that the average person has about 20 genes with loss-of-function mutations—many more than previously suspected.

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image: Double the Mutations

Double the Mutations

By | January 30, 2012

Irradiated sperm of young male mice induce mutations in eggs upon fertilization, a phenomenon that may pose risks for the children of cancer survivors.

12 Comments

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