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image: Low Mutation Rate in iPSCs

Low Mutation Rate in iPSCs

By | April 11, 2016

The mutation rate in induced pluripotent stem cells is 10 times lower than in somatic cells, scientists show.


image: Estimating Epigenetic Mutation Rates

Estimating Epigenetic Mutation Rates

By | May 11, 2015

Generation-spanning maps of Arabidopsis thaliana DNA methylation allow researchers to compute how quickly epigenetic marks appear and disappear in the plant’s genome.


image: Ebola Mutation Rate Quibble

Ebola Mutation Rate Quibble

By | March 27, 2015

A study suggests that the virus may not be evolving as quickly as a previous group estimated.


image: Stem Cell Divisions Help Explain Cancer Risk

Stem Cell Divisions Help Explain Cancer Risk

By | January 1, 2015

An analysis of 31 tissues finds that random mutations acquired during stem cell divisions correlate with lifetime cancer risk—more so than heritable mutations and environmental factors combined.  


image: Identifying Spurious Cancer Mutations

Identifying Spurious Cancer Mutations

By | June 19, 2013

Researchers reveal why analyses of cancer-causing mutations are riddled with false positives and demonstrate a new approach that eliminates the problem.


image: Ginormous Genome

Ginormous Genome

By | May 1, 2012

Researchers find organisms with huge genomes with high mutation rates, overturning a common expectation in evolutionary biology.


image: Our Missing Genes

Our Missing Genes

By | February 17, 2012

New research suggests that the average person has about 20 genes with loss-of-function mutations—many more than previously suspected.


image: Double the Mutations

Double the Mutations

By | January 30, 2012

Irradiated sperm of young male mice induce mutations in eggs upon fertilization, a phenomenon that may pose risks for the children of cancer survivors.


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