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image: Sex Differences in Immune Response

Sex Differences in Immune Response

By | June 21, 2016

Female mice lacking an immune receptor are better than males at fighting certain viral infections.

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Post-publication peer review prompts the authors to clarify the ages of mice used in their experiments and share additional data.

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image: Dying Light Marks the Spot

Dying Light Marks the Spot

By | March 29, 2016

Drug-delivering nanoparticles designed to glow when their target cells die can report on the effectiveness of cancer therapies within just a few hours of treatment, a mouse study shows.

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image: Obesity, Diabetes, and Epigenetic Inheritance

Obesity, Diabetes, and Epigenetic Inheritance

By | March 14, 2016

Disease risk can be transmitted epigenetically via egg and sperm cells, a mouse study shows.

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image: X Marks the Sex-Skewed Spot

X Marks the Sex-Skewed Spot

By | March 7, 2016

Alterations in epigenetic markers on the X chromosome may be why males outnumber females among murine offspring bred through in vitro fertilization.

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image: Toward Making Sperm in the Lab

Toward Making Sperm in the Lab

By | February 25, 2016

Researchers devise a technique for creating gametes from murine embryonic stem cells.

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image: Insulin-Producing Mini Stomachs

Insulin-Producing Mini Stomachs

By | February 22, 2016

Scientists grow gastric organs in vitro that can restore insulin production when transplanted into mice.

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image: Turning Tumor Cells Against Cancer

Turning Tumor Cells Against Cancer

By | February 8, 2016

In mice, cancer cells genetically modified to express an anticancer cytokine home to tumors and can reduce their growth. 

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image: Slowing Aging

Slowing Aging

By | February 5, 2016

The removal of senescent cells in mice leads to an increased lifespan and later onset of age-linked diseases, scientists show.

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image: Inside a Lab Mouse’s High-Fat Diet

Inside a Lab Mouse’s High-Fat Diet

By | November 23, 2015

Researchers should pay closer attention to the diets they use to study obesity in mice, experts advise.

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