mouse study

Researchers improve on a technique to use a light-stimulated small molecule to confer longer-term photosensitivity to the retinal cells of blind mice.

A mouse study reveals a causal link between changes in intestinal microbiota and increasing inflammation as the rodents age.

A protein secreted by osteoblasts crosses the blood-brain barrier to regulate hunger in mice.

Examining both male and female model organisms is worth the extra effort and added costs, most experts maintain, but whether the results translate to human studies is less clear.
 

The virus may persist in testes even after the infection is no longer detectable in blood, leading to sexual transmission of the disease and fertility impairments.

Researchers produce functional organs composed of both mouse and rat cells.

Ethanol triggers starvation-activated neurons, leading mice to overeat. 

In a mouse model, researchers mitigated three Alzheimer’s disease–associated symptoms by stimulating gamma waves with light.

In vivo imaging reveals how grafted embryonic brain cells grow, connect, and mature into contributing members of damaged visual pathways in adult mice.

Type I interferon organizes several immune mechanisms to suppress B cell responses to a chronic viral infection.

Mice that live in a more-stimulating environment for two weeks appear to develop a more-inflammatory immune state that might help protect the animals against infection. 

Murine embryos undergoing first cell division can reprogram injected sperm and develop normally. 

Mutations that arise during stem cell division contribute to the development of cancers in a variety of organs, according to a study.

Limiting food intake leads to the conversion of white fat cells into more metabolically active brown fat cells through an immune response, a mouse study shows.

Disrupting the light/dark cycles of pregnant mice, researchers observe detrimental effects in the mouths of the animals’ pups.

A mouse study shows that the virus has tropism for adult proliferative neural progenitor cells and immature neurons.

Female mice lacking an immune receptor are better than males at fighting certain viral infections.

Post-publication peer review prompts the authors to clarify the ages of mice used in their experiments and share additional data.

Drug-delivering nanoparticles designed to glow when their target cells die can report on the effectiveness of cancer therapies within just a few hours of treatment, a mouse study shows.

Disease risk can be transmitted epigenetically via egg and sperm cells, a mouse study shows.