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Infographic: Is Cellular Waste at the Root of Parkinson’s Disease?
Infographic: Is Cellular Waste at the Root of Parkinson’s Disease?
Damage to the lysosome, the organelle that removes excess proteins, lipids, and other materials, might be at the root of the disease.
Infographic: Is Cellular Waste at the Root of Parkinson’s Disease?
Infographic: Is Cellular Waste at the Root of Parkinson’s Disease?

Damage to the lysosome, the organelle that removes excess proteins, lipids, and other materials, might be at the root of the disease.

Damage to the lysosome, the organelle that removes excess proteins, lipids, and other materials, might be at the root of the disease.

neurodegeneration, disease & medicine

Tau Pathology Present Decades After a Single Brain Injury
Ruth Williams | Sep 9, 2019 | 3 min read
Patients who suffer a traumatic brain injury may exhibit abnormally abundant tau protein many years later, a new in vivo imaging technique reveals.
human macrophage
Image of the Day: Alzheimer’s Genes
Nicoletta Lanese | Aug 19, 2019 | 1 min read
Mutations within the MS4A gene cluster have been linked to changes in protein levels that affect disease risk.
Commensal Bacterium Reduces ALS Symptoms in Mice
Jef Akst | Jul 24, 2019 | 2 min read
Boosting the levels of Akkermansia muciniphila in mouse guts slowed the progression of an ALS-like disease, while two other microbiome members were associated with more severe symptoms.
ted dawson alpha-synuclein parkinson's disease model gut vagus nerve dopamine johns hopkins school of medicine
Mouse Model Shows How Parkinson’s Disease Begins in the Gut
Emma Yasinski | Jun 26, 2019 | 3 min read
Johns Hopkins’s Ted Dawson discusses his lab’s demonstration that misfolded α-synuclein can move from the stomach to the brain and cause physical and cognitive symptoms.
Pro Football Players Die at a Higher Rate than Pro Baseball Players
Jef Akst | May 28, 2019 | 1 min read
A comparison of thousands of former athletes in the two sports finds that NFL players were more likely than MLB players to die from cardiovascular and neurodegenerative diseases, in particular.
Rapidly Flashing Lights and Sounds Reduces Alzheimer’s in Mice
Jef Akst | Mar 15, 2019 | 2 min read
Exposing mice to an hour of 40-hertz stimuli every day for a week reduced levels of amyloid-β plaques and tau protein, and improved cognition.
brain virus infographic the scientist
Infographic: Viruses on the Brain
Ashley Yeager | Mar 1, 2019 | 1 min read
Pathogens can take various routes to pass the blood brain barrier and damage cells.
viral brain feature the scientist
Can the Flu and Other Viruses Cause Neurodegeneration?
Ashley Yeager | Mar 1, 2019 | 10+ min read
Scientists may need to seriously reconsider the cast-aside hypothesis that pathogens can play a part in diseases such as Alzheimer’s and Parkinson’s.
Gum Disease Could Drive Alzheimer’s: Study
Ashley Yeager | Jan 24, 2019 | 2 min read
An enzyme of the bacteria Porphyromonas gingivalis has been found in the brains of patients with the disorder, and causes neurodegeneration in mice.
Protein Changes Detected in Blood Years Before Alzheimer’s Onset
Jef Akst | Jan 21, 2019 | 2 min read
The observation could pave the way for a blood test to predict disease progression in people with a genetic predisposition to developing the neurodegenerative disorder.
Infographic: Human Endogenous Retroviruses and Disease
Katarina Zimmer | Jan 1, 2019 | 3 min read
Human endogenous retroviruses that colonized vertebrate DNA millions of years ago have long been dismissed as junk DNA, but researchers now know that they may play important roles in cancer, neurodegeneration, and other ailments.
Dopamine Neuron Implants Ease Parkinsonā€™s Symptoms in Monkeys
Sukanya Charuchandra | Jun 20, 2018 | 3 min read
The stem cell–derived transplants were stable for 24 months and led to wide-ranging behavioral improvements in the monkeys.  
Researchers Succeed in Keeping Disembodied Pig Brains Alive
Catherine Offord | May 1, 2018 | 2 min read
The organs showed neural activity for up to 36 hours, adding fuel to discussions about the ethics of future neuroscientific research.
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