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image: Five Life-Science MacArthur Winners

Five Life-Science MacArthur Winners

By | September 22, 2011

This year’s winners research topics ranging from stem cell regulation to brain damage from football injuries.

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image: Behavior Brief

Behavior Brief

By | September 21, 2011

A round-up of recent discoveries in behavior research

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image: Top 7 in Ecology

Top 7 in Ecology

By | September 8, 2011

A snapshot of the most highly ranked articles in ecology, from Faculty of 1000

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image: Opinion: The Invasive Ideology

Opinion: The Invasive Ideology

By | September 7, 2011

Biologists and conservationists are too eager to demonize non-native species.

48 Comments

image: Secrets of Aging

Secrets of Aging

By | September 1, 2011

What does a normally aging brain look like? Are diseases of aging such as Alzheimer’s inevitable?

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image: What Causes Alzheimer’s?

What Causes Alzheimer’s?

By | September 1, 2011

Researchers and pharma companies have tried to attack this disease by reducing amyloid plaques, but inflammation may be the real culprit.

39 Comments

image: Lost in Space

Lost in Space

By | September 1, 2011

Looking for a more realistic way to study memory, we turned to place cells­­—­a network of cells that record a rat’s memory of an environment. 

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image: Molecular Learning

Molecular Learning

By | September 1, 2011

Long-term potentiation (LTP), discovered in the 1970s, was later shown to be the molecular basis of memory. 

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image: The Seat of Memory

The Seat of Memory

By | September 1, 2011

Early on, researchers had learned that the hippocampus was the structure in the brain where long-term memories were created and stored, but it was not known whether the different cell types within this structure might be more or less susceptible to the aging process.

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image: The Cytokine Cycle

The Cytokine Cycle

By | September 1, 2011

The initiating cause of Alzheimer’s disease is still unknown. However, from our studies it’s clear that many types of neuronal damage—­­from traumatic brain injury, to epilepsy, infection, or genetic predisposition—­can activate brain immune cells—microglia and astrocytes-- promoting them to produce IL-1 and S100 inflammatory cytokines.

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