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» neurodegeneration and evolution

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image: The Mosaic Pre-Man

The Mosaic Pre-Man

By | September 8, 2011

Newly excavated Australopithecus sediba fossils exhibit a mixture of primitive and more modern features.

15 Comments

image: Genetics Paper Retracted

Genetics Paper Retracted

By | September 2, 2011

Due to statistical errors, a Science paper claiming that mutation is responsible for genetic variation is retracted.

9 Comments

image: Secrets of Aging

Secrets of Aging

By | September 1, 2011

What does a normally aging brain look like? Are diseases of aging such as Alzheimer’s inevitable?

78 Comments

image: What Causes Alzheimer’s?

What Causes Alzheimer’s?

By | September 1, 2011

Researchers and pharma companies have tried to attack this disease by reducing amyloid plaques, but inflammation may be the real culprit.

39 Comments

image: Corina Tarnita: The Ant Mathematician

Corina Tarnita: The Ant Mathematician

By | September 1, 2011

Junior Fellow, Harvard Society of Fellows, Harvard University. Age: 28

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image: Lost in Space

Lost in Space

By | September 1, 2011

Looking for a more realistic way to study memory, we turned to place cells­­—­a network of cells that record a rat’s memory of an environment. 

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image: Molecular Learning

Molecular Learning

By | September 1, 2011

Long-term potentiation (LTP), discovered in the 1970s, was later shown to be the molecular basis of memory. 

0 Comments

image: Octophilosophy

Octophilosophy

By | September 1, 2011

When it comes to studying cephalopod brains and behavior, it helps to have a philosopher around.

30 Comments

image: The Seat of Memory

The Seat of Memory

By | September 1, 2011

Early on, researchers had learned that the hippocampus was the structure in the brain where long-term memories were created and stored, but it was not known whether the different cell types within this structure might be more or less susceptible to the aging process.

0 Comments

image: The Cytokine Cycle

The Cytokine Cycle

By | September 1, 2011

The initiating cause of Alzheimer’s disease is still unknown. However, from our studies it’s clear that many types of neuronal damage—­­from traumatic brain injury, to epilepsy, infection, or genetic predisposition—­can activate brain immune cells—microglia and astrocytes-- promoting them to produce IL-1 and S100 inflammatory cytokines.

12 Comments

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