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image: Toggling Between Life and Death

Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.

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image: Yvonne Saenger: Immunotherapy Pioneer

Yvonne Saenger: Immunotherapy Pioneer

By | April 1, 2015

Assistant Professor, Department of Medicine, Columbia University. Age: 41

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image: From Many, One

From Many, One

By | April 1, 2015

Diverse mammals, including humans, have been found to carry distinct genomes in their cells. What does such genetic chimerism mean for health and disease?

4 Comments

image: Resisting Cancer

Resisting Cancer

By | April 1, 2015

If one out of three people develops cancer, that means two others don’t. Understanding why could lead to insights relevant to prevention and treatment.

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image: Pain and Itch Neurons Found

Pain and Itch Neurons Found

By | March 31, 2015

Inhibitory nerve cells in the spinal cord stop the transmission of pain and itch signals in mice.

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image: Short, Strong Signals

Short, Strong Signals

By | March 25, 2015

Methylation increases both the activity and instability of the signaling protein Notch.

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image: Opinion: Can the Brain Be Trained?

Opinion: Can the Brain Be Trained?

By | March 23, 2015

Online brain-training is gaining popularity, but so far little evidence exists to support claims of improved cognition.

3 Comments

image: Irisin Skepticism Goes Way Back

Irisin Skepticism Goes Way Back

By | March 18, 2015

Post-publication peer reviewers had questioned data about the supposed fat-browning enzyme from the get-go.

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image: Call for Germline Editing Moratorium

Call for Germline Editing Moratorium

By | March 13, 2015

In response to speculation that groups have edited the DNA of human embryos, researchers request that gene editing of human reproductive cells be halted.

2 Comments

image: Stimulating Neurons with Light and Gold

Stimulating Neurons with Light and Gold

By | March 12, 2015

Researchers develop a technique to trigger neural activity in culture using light to heat gold nanoparticles.

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The Scientist
The Scientist