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tag mouse model evolution immunology ecology

In Evolution's Garden
Megan Scudellari | Jun 1, 2013 | 9 min read
Raising one evolutionary question after another, Brandon Gaut has harvested a crop of novel findings about how plant genomes evolve.
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
Illuminating Behaviors
Douglas Steinberg | Jun 1, 2003 | 6 min read
Courtesy of Genevieve Anderson If not for Nobel laureates Thomas Hunt Morgan, Eric R. Kandel, and Sydney Brenner, the notion of a general behavioral model might seem odd. Behaviors, after all, are determined by an animal's evolutionary history and ecological niche. They are often idiosyncratic, shared in detail only by closely related species. But, thanks to Morgan's research in the early 20th century, and Kandel's and Brenner's work over the past 35 years, the fly Drosophila melanogaster, t
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
black lab mice microbiome
Microbes May Take Some of the Blame for the Reproducibility Crisis
Emma Yasinski | Apr 5, 2019 | 4 min read
Scientists find varied microbiota among the same strain of mice from four vendors—and that variability affects their susceptibility to infection.
Targeting Antibiotic-Resistant Bacteria with CRISPR and Phages
Anna Azvolinsky | May 18, 2015 | 3 min read
Researchers develop a CRISPR-based, two-phage system that sensitizes resistant bacteria to antibiotics and selectively kills any remaining drug-resistant bugs. 
Lurking in the Shadows
Bob Grant | Dec 1, 2014 | 10+ min read
Bats harbor diverse pathogens, including Ebola, Marburg, SARS, and MERS viruses. Understanding why could help researchers stymie deadly emerging diseases.
"Big Cross" Lands Sticklebacks in the Spotlight
David Secko | Nov 7, 2004 | 5 min read
Marine threespine sticklebacks haven't morphologically changed in an estimated 10 million years, but their freshwater offshoots show no signs of slowing down. These 5-cm-long, freshwater fish have undergone a recent evolutionary change, variably losing their calcified body armor and retractable pelvic and dorsal spines. Remarkably, isolated marine and freshwater sticklebacks can be hybridized in the laboratory, a fact that is allowing researchers to analyze the genetics behind their natural dive
The Hidden Side of Sex
Patricia L.R. Brennan | Jul 1, 2014 | 10+ min read
Sexual selection doesn’t end when females choose a mate. Females and males of many animal species employ an array of tactics to stack the deck in their reproductive favor.
Pufferfish Genomes Probe Human Genes
Ricki Lewis | Mar 17, 2002 | 7 min read
It may be humbling to think that humans have much in common with pufferfish, but at the genome level, the two are practically kissing cousins. "In terms of gene complement, we are at least 90% similar—probably higher. There are big differences in gene expression levels and alternate transcripts, but if you're talking about diversity, number and types of proteins, then it's pretty difficult to tell us apart," says Greg Elgar, group leader of the Fugu genome project at the Medical Research C

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