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The Scientist

» grant, immunology and cell & molecular biology

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image: Blood-Gut Barrier

Blood-Gut Barrier

By | November 12, 2015

Scientists identify a barrier in mice between the intestine and its blood supply, and suggest how Salmonella sneaks through it.

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image: Microbes Play Role in Anti-Tumor Response

Microbes Play Role in Anti-Tumor Response

By | November 5, 2015

Gut microbiome composition can influence the effectiveness of cancer immunotherapy in mice.

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image: New Route to Hearing Loss Mapped

New Route to Hearing Loss Mapped

By | November 5, 2015

Deficiency in a protein called pejvakin makes inner ear cells more vulnerable to sound, unable to brace themselves against oxidative stress stimulated by noise. 

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image: Ebola’s Immune Escape

Ebola’s Immune Escape

By | November 3, 2015

The virus can persist in several tissues where the immune system is less active. Researchers are working to better understand this phenomenon and how it can stall the clearing of Ebola in survivors.

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image: Adding Padding

Adding Padding

By | November 1, 2015

Adipogenesis in mice has alternating genetic requirements throughout the animals’ lives.

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image: Fanning the Flames

Fanning the Flames

By | November 1, 2015

Obesity triggers a fatty acid synthesis pathway, which in turn helps drive T cell differentiation and inflammation.

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image: Breaking the Cancer-Obesity Link

Breaking the Cancer-Obesity Link

By , and | November 1, 2015

Obese people are at higher risk for developing cancer, have worse prognoses once diagnosed, and are often resistant to chemotherapy regimens. The question is, Why?

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image: Obesogens

Obesogens

By | November 1, 2015

Low doses of environmental chemicals can make animals gain weight. Whether they do the same to humans is a thorny issue.

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image: A Complex Disorder

A Complex Disorder

By , and | November 1, 2015

Factors that likely contribute to obesity include disruptions to intercellular signaling, increased inflammation, and changes to the gut microbiome.  

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image: Fat Factors

Fat Factors

By | November 1, 2015

A mouse's exposure to certain environmental chemicals can lead the animal—and its offspring and grandoffspring—to be overweight.

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