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tag sex chromosome neuroscience disease medicine

Illustration showing a puzzle piece of DNA being removed
Large Scientific Collaborations Aim to Complete Human Genome
Brianna Chrisman and Jordan Eizenga | Sep 1, 2022 | 10+ min read
Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.
Sex Differences in the Brain
Margaret M. McCarthy | Oct 1, 2015 | 10+ min read
How male and female brains diverge is a hotly debated topic, but the study of model organisms points to differences that cannot be ignored.
X and Y Chromosomes Concern More Than Reproduction
Karen Young Kreeger | Feb 3, 2002 | 6 min read
Editor's Note: This is the third article in a series on sex-based differences in the biology of males and females. Future articles in the series will cover sex-based differences in autoimmunity, drug metabolism, and life expectancy. While responses to "What's the difference between men and women?" might evoke answers about reproductive plumbing and hormones, researchers are unearthing some subtle, genomic reasons for the differences. So far, the linchpins to finding these genomic variations seem
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
How Manipulating Rodent Memories Can Elucidate Neurological Function
Amber Dance | May 1, 2020 | 10+ min read
Strategies to make lab animals forget, remember, or experience false recollections probe how memory works, and may inspire treatments for neurological diseases.
Week in Review: June 29–July 3
Jef Akst | Jul 3, 2015 | 3 min read
Sex differences in processing pain; clue in flu vaccine–narcolepsy link found; early antibiotic use affects the gut microbiome; lizard sex determined by genes, then temperature
Those We Lost in 2019
Ashley Yeager | Dec 30, 2019 | 6 min read
The scientific community said goodbye to Sydney Brenner, Paul Greengard, Patricia Bath, and a number of other leading researchers this year.
Contributors
The Scientist Staff | May 1, 2012 | 2 min read
Meet some of the people featured in the April 2012 issue of The Scientist.
Telomere Findings May Yield Tips For Treating Cancer, Geriatric Disorders
Ricki Lewis | Feb 18, 1996 | 7 min read
Geriatric Disorders Author: Ricki Lewis SIDEBAR : TELOMERE BIOLOGY RESOURCES Chromosome tips, called telomeres, have long fascinated geneticists because they protect chromosomes from degradation. And recent research has revealed another vital role for telomeres: As they shrink with each cell division, they keep a biochemical tally of the number of divisions remaining in a cell's lifetime. If this precise control goes awry, the biochemical consequences could be dire, such as uncontrolled growt
Preimplantation Genetic Diagnosis: The Next Big Thing?
Ricki Lewis | Nov 12, 2000 | 9 min read
Courtesy of David Hill, ART Reproductive Center Inc.Two separated blastomeres subjected to FISH analysis to check the chromosomes. In early October, preimplantation genetic diagnosis (PGD) made headlines when a Colorado couple used assisted reproductive technology (ART) to have a baby named Adam, whose umbilical cord stem cells could cure his six-year-old sister Molly's Fanconi anemia.1 When Adam Nash was a ball of blastomere cells, researchers at the Reproductive Genetics Institute at Illinois

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