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tag cryopreservation culture disease medicine

bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Professor Sir Ian Wilmut with Dolly the sheep
Ian Wilmut, Famed Scientist Who Led the Creation of Dolly the Sheep, Died at 79
Shelby Bradford, PhD | Sep 12, 2023 | 3 min read
Knighted in 2008, Sir Ian Wilmut revolutionized the field of cloning, stem cell research, and regenerative medicine.
Image of pancreatic organoids under a microscope with immunofluorescent staining
Pancreatic Organoids Take the Stage
Laura Tran, PhD | Dec 1, 2023 | 2 min read
Meritxell Huch tackled her pipedream of growing three-dimensional pancreatic tissue in a dish.
a newly hatched mosquito sits on top of water, with its discarded cocoon floating below
In Vitro Malaria Sporozoite Production May Lead to Cheaper Vaccines
Katherine Irving | Jan 20, 2023 | 4 min read
A method for culturing the infectious stage of the Plasmodium lifecycle could increase malaria vaccine production efficiency by tenfold, study authors say.
A microscopy image of an apical-out colon organoid that was produced using MilliporeSigma’s protocol.
Turning Organoids Inside Out 
The Scientist, MilliporeSigma, and Hub Organoids | Aug 15, 2023 | 4 min read
Discover how a new procedure reverses the polarity of typical basolateral-out organoids to form versatile apical-out organoids.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Patient-derived colon organoids from a healthy individual
Generating Mini-Guts for Drug Screening
The Scientist and MilliporeSigma | Dec 16, 2022 | 4 min read
Human gut organoids facilitate precise disease modeling and power high-throughput drug development efforts.
Mini organs in a dish
What Are Organoids and How Are They Made?
Jennifer Zieba, PhD | Aug 11, 2022 | 8 min read
Miniaturized, in vitro versions of organs provide insights into disease and development.
Week in Review: April 28–May 2
Tracy Vence | May 2, 2014 | 3 min read
Male scientists stress mice out; using SCNT to reprogram adult cells; acetate can reach mouse brain, reduce appetite; WHO sounds “post-antibiotic era” alarm
Brain cell in purple on a black background. Arc mRNAs are labeled green and are mainly localized in the cell nucleus and in the dendrites.
Short-lived Molecules Support Long-term Memory 
Alejandra Manjarrez, PhD | Jun 6, 2023 | 3 min read
A gene essential for information storage in the brain engages an autoregulatory feedback loop to consolidate memory.

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