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image: Silencing Surprise

Silencing Surprise

By | June 1, 2015

A chromatin remodeler in embryonic stem cells clears the DNA for mRNA transcription while stifling the expression of noncoding transcripts.

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image: DNA Loop-the-Loops

DNA Loop-the-Loops

By | December 11, 2014

A new full-genome map indicates how DNA is folded within the nuclei of human cells.

5 Comments

image: Modified CRISPR Expands Targets

Modified CRISPR Expands Targets

By | August 8, 2014

Tweaking the expression of guide RNAs used in CRISPR genome editing broadens the repertoire of target sites.

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image: Exploring the Roles of Enhancer RNAs

Exploring the Roles of Enhancer RNAs

By | May 7, 2014

Scientists have recently discovered that enhancers are often transcribed into RNAs. But they’re still not sure what, if anything, these eRNAs do.

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image: Enhancer and Promoter Atlases

Enhancer and Promoter Atlases

By | March 26, 2014

Consortium annotates the human genome with cell type-specific information about transcription start sites, active enhancers, and their expression throughout the body.

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image: Promoting Death

Promoting Death

By | March 1, 2012

Editor's choice in biochemistry

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