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tag genetic manipulation evolution disease medicine

Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
A bat flying in a dark cave
Turning on the Bat Signal
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
How Manipulating Rodent Memories Can Elucidate Neurological Function
Amber Dance | May 1, 2020 | 10+ min read
Strategies to make lab animals forget, remember, or experience false recollections probe how memory works, and may inspire treatments for neurological diseases.
3d rendered medically accurate illustration of a human embryo anatomy
The Ephemeral Life of the Placenta
Danielle Gerhard, PhD | Dec 4, 2023 | 10+ min read
Recent advances in modeling the human placenta, the least understood organ, may inform placental disorders like preeclampsia.
The Proteasome: A Powerful Target for Manipulating Protein Levels
John Hines and Craig M. Crews | May 1, 2017 | 10+ min read
The proteasome’s ability to target and degrade specific proteins is proving useful to researchers studying protein function or developing treatments for diseases.
blue-gloved hands pipetting from test tube
What’s Next for Ancient DNA Studies After the Nobel?
Mary Prendergast, The Conversation | Oct 5, 2022 | 4 min read
The award highlights tremendous opportunities for aDNA as well as challenges related to rapid growth, equity, and misinformation.
Diseases by Design
Jennifer Fisher Wilson | Jun 1, 2003 | 6 min read
Jacob Halaska, ©Index Stock Imagery Researchers like mice. US government statistics reveal that the whiskered ones show up in 90% of all experiments. Mice come cheap, procreate often, and die fairly quickly. And although evolution separates mouse from human by an estimated 75 to 100 million years, biologically and genetically speaking, they share a lot; as much as 85% of the DNA in mice is the same in humans. The research ground that mice have domineered for a century, however, is reced
an immune cell in blood
Why Viral Infections Are More Severe in People with Down Syndrome
Andy Carstens | Oct 14, 2022 | 6 min read
In people with the genetic condition, inflammation can cause a mild infection to snowball out of control, a study finds.
Photo of Ana Marija Jakšic
Ana Marija Jakšić Shapes Fruit Fly Brains
Chloe Tenn | Apr 18, 2022 | 3 min read
The Swiss Federal Institute of Technology Lausanne evolutionary neurobiologist is using Drosophila to investigate how organisms adapt to novel environments.

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