Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 

Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.

Using a circuit-based system, scientists determined the ideal transcription factor levels to promote the successful reprogramming of fibroblasts into induced pluripotent stem cells.

Two studies find adult pancreatic cells maintain islet population, contradicting a hypothesis that regeneration relies on stem cells

Endometrial organoids and single cell analyses helped uncover the molecular mechanisms of a rare uterine condition.

The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.

Adult stem cells become slower at dividing as they age because they get less efficient at sensing their microenvironment, according to a study to be published in Nature tomorrow. The findings suggest a mechanism to explain why production of adult stem cells such as sperm drops as an organism gets older. "I think this is a fantastic piece of work that begins to explain" how adult stem cells age, said linkurl:Leanne Jones,;http://www-biology.ucsd.edu/faculty/jonesl.html a stem cell biologist at

With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.

By mechanically inducing the expansion of cranial sutures in young adult mice, researchers stimulated stem cell proliferation that is key to healing bone injuries.

Most of the human induced pluripotent stem cells stored at major cell line repositories and used in research harbor thousands of DNA errors, a study finds, highlighting the need for improved quality control measures.