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image: Making CAR T-Cell Therapy Safer

Making CAR T-Cell Therapy Safer

By | April 1, 2017

Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.

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image: Neoantigens Enable Personalized Cancer Immunotherapy

Neoantigens Enable Personalized Cancer Immunotherapy

By | April 1, 2017

Tumors’ mutations can encode the seeds of their own destruction, in the form of immunogenic peptides recognized by T cells.

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image: Infographic: Antibody Cancer Therapy

Infographic: Antibody Cancer Therapy

By | April 1, 2017

An experimental technique removes T cells that aid in vitro tumor growth.

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image: Infographic: Targeting Cancer Antigens

Infographic: Targeting Cancer Antigens

By | April 1, 2017

Neoantigens may serve as valuable targets for new immunotherapies.

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image: Targeting Tregs Halts Cancer’s Immune Helpers

Targeting Tregs Halts Cancer’s Immune Helpers

By | April 1, 2017

New monoclonal antibodies kill both cancer-promoting immunosuppressive cells and tumor cells in culture.

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image: Anti-Flavivirus Antibodies Enhance Zika Infection in Mice

Anti-Flavivirus Antibodies Enhance Zika Infection in Mice

By | March 30, 2017

Researchers report evidence of antibody-dependent enhancement in a Zika-infected, immunocompromised mouse model.

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image: Experimental MERS Treatments Target Host Cell Receptor

Experimental MERS Treatments Target Host Cell Receptor

By | March 30, 2017

Researchers are searching for ways to prevent the coronavirus from attaching to DPP-4 receptors, blocking it from invading and replicating within host cells.

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image: Image of the Day: Tubular Origins

Image of the Day: Tubular Origins

By | March 23, 2017

Murine neural tubes, with each image highlighting a different embryonic tissue type (blue). The neural tube itself (left) grows into the brain, spine, and nerves, while the mesoderm (middle) develops into other organs, and the ectoderm (right) forms skin, teeth, and hair.

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image: Macchiarini Retracts Another Paper

Macchiarini Retracts Another Paper

By | March 22, 2017

The embattled thoracic surgeon blames his former employer, the Karolinska Institute, for losing data related to the retracted research.

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Researchers report growing a mouse embryo using two types of early stem cells.

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