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tag national academy of science disease medicine neuroscience evolution

Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Neuroscience/ Alzheimer's Disease Research
Karen Young Kreeger | Feb 18, 1996 | 2 min read
Comments by Virginia M.-Y. Lee and John Q. Trojanowski, University of Pennsylvania School of Medicine New Twist On Tangles: Research conducted by Penn's John Trojanowski and Virginia Lee suggests that phosphatases may be "lazy," or inactive, in Alzheimer's tangles. This paper offers a new way of looking at the formation of tangles-a twisted neuronal knot of paired helical filaments (PHFs). PHFs are one of the two primary diagnostic features found in the brains of Alzheimer's disease (AD) pat
National Academy Bestows Honors On 18 Accomplished Researchers
Edward Silverman | Apr 27, 1997 | 8 min read
Eighteen accomplished researchers, including a 91-year-old endocrinologist who's known affectionately as "the George Burns of science," are being honored for their achievements at the 134th annual meeting of the National Academy of Sciences (NAS), scheduled for April 28 in Washington, D.C. They will be feted during an event that will include the election of new academy members and the induction of members elected last year (T.W. Durso, The Scientist, May 27, 1996, page 3). The academy's highes
National Academies Recommend Field Trials for Gene Drives
Catherine Offord | Jun 8, 2016 | 2 min read
A report advises that, although gene-drive modified organisms are not ready to be released, carefully controlled field trials could go ahead.
ethics, bioethics, brain organoid, chimera, cell transplant, Q&A, report, NIH, NAS, neuroscience, Techniques, disease & medicine, immunology, psychiatric conditions
New Report Dissects Ethics of Emerging Human Brain Cell Models
Amanda Heidt | Apr 12, 2021 | 5 min read
The National Academies’ report touches on ethical issues raised by new technologies such as brain organoids and human-animal chimeras, and suggests that current regulatory oversight is sufficient.
Infant hands holding bottle of milk on light blue floor background.
Myo-inositol in Human Breast Milk Improves Brain Connectivity
Charlene Lancaster, PhD | Oct 16, 2023 | 4 min read
Researchers find that the sugar myo-inositol is abundant early in lactation and increases synapse size and abundance in the developing brain.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Neuroscience
The Scientist Staff | Jun 21, 1992 | 2 min read
D.S. Bredt, P.M. Hwang, S.H. Snyder, "Localization of nitric oxide synthase indicating a neural role for nitric oxide," Nature, 347:768-70, 1990. Solomon Snyder (Johns Hopkins University School of Medicine, Baltimore): "Nitric oxide appears to be responsible for the ability of macrophages to kill tumor cells and bacteria and makes it possible for substances such as acetylcholine to cause blood vessels to dilate. Acetylcholine, acting at receptors on endothelial cells, triggers the formation of
Science Needs Private Support
Bruce Alberts | Dec 6, 1998 | 3 min read
The National Academy of Sciences (NAS), the National Academy of Engineering (NAE), the Institute of Medicine (IOM)--along with our "operating arm," the National Research Council (NRC)--are private, independent nonprofit organizations. Most of the work that we do is funded by the federal government in our role as science advisers to the nation. This tradition of service reaches back to our 1863 charter, and providing independent advice to our government remains the central role of the NAS, NAE,
Can Viruses in the Genome Cause Disease?
Katarina Zimmer | Jan 1, 2019 | 10+ min read
Clinical trials that target human endogenous retroviruses to treat multiple sclerosis, ALS, and other ailments are underway, but many questions remain about how these sequences may disrupt our biology.

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