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tag appeal disease medicine

Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Landmarks of Human Variations
Maria Anderson | May 9, 2004 | 5 min read
BUILDING BLOCKS:© 2001 AAASAlong a 106-kilobase stretch of human chromosome 21, one study found that 18 haplotype blocks represent a segment of 147 SNPs from 20 individual copies of the chromosome. One block, containing 26 SNPs and spanning 19 kilobases, is detailed at right. The four most common haplotypes, occurring in 16 of the 20 chromosomes sampled, can be identified by two tag SNPs (bottom right). (Adapted from N. Patil, Science, 294:1719–23, 2001)The myriad medical breakthrough
Flux and Uncertainty in the CRISPR Patent Landscape
Aggie Mika | Oct 1, 2017 | 10 min read
The battle for the control of the intellectual property surrounding CRISPR-Cas9 is as storied and nuanced as the technology itself.
The Value of Your Genome
James P. Evans and Jonathan S. Berg | Dec 1, 2012 | 3 min read
Genome sequencing: it’s not for everyone
Biotech Faces Evolving Patent System
Douglas Steinberg | Mar 5, 2000 | 8 min read
Like medieval alchemists, modern biologists apply intricate, esoteric protocols to lowly matter, such as bacteria and rodents. Unlike alchemists, biologists successfully transmute these creatures into gold--disease-fighting pharmaceuticals and profits accruing from them. An indispensable ingredient in this dross-to-drug process is patent protection, which preserves monopoly and attracts investment. Unfortunately, the patent system isn't as ideal a catalyst as the chimerical philosopher's stone s
Lab 2.0
Hayley Dunning | Dec 1, 2012 | 8 min read
Apps and software for improving lab productivity
The 2011 Labby Multimedia Awards
Jessica P. Johnson | Sep 1, 2011 | 6 min read
Introducing the winners of our second annual "Labbies" awards
Longevity
Jill Adams(juadams@the-scientist.com) | May 8, 2005 | 7 min read
During autophagy-literally "self-eating"-cells deliver cytoplasmic constituents, including whole organelles, to the lysosome for degradation.
Biosense or Biononsense
Katherine Eban | Apr 1, 2007 | 10+ min read
Biosense or Biononsense? Years of development and hundreds of millions of dollars later, what has the CDC's syndromic surveillance program accomplished?By Katherine Eban ARTICLE EXTRAS Syndromic Surveillance in California It was two days before Thanksgiving 2004, when an epidemiologist in New Jersey's public health agency picked up a heart-stopping electronic message. The
Labs Scurry To Meet Animal Care Mandate
Marcia Clemmitt | Jul 21, 1991 | 7 min read
USDA's deadline nears, and scientists struggle to reconcile their research priorities with new regulations Laboratories throughout the United States that use animals for research are rushing to meet new federal regulations affecting the welfare of animals used for research. The regulations cover exercise for dogs, improved housing for cats, and the psychological well-being of nonhuman primates. The rules require labs to have on hand, ready for inspection, plans that comply with these regulati

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