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image: Location, Location, Location

Location, Location, Location

By | April 1, 2017

Since first proposing that a cell’s function and biology depend on its surroundings, Mina Bissell continues to probe the role of the extracellular matrix.

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image: Making CAR T-Cell Therapy Safer

Making CAR T-Cell Therapy Safer

By | April 1, 2017

Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.

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image: Notable Science Quotes

Notable Science Quotes

By | April 1, 2017

Eugene Garfield, the cancer moonshot, employee genetic testing, and more

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Measuring PD-L1 levels was a great start. Now we need to quantify more protein biomarkers, assess the tumor mutational landscape, and examine immune cell signatures, too.

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image: Starvation Response Triggers Melanoma Invasion

Starvation Response Triggers Melanoma Invasion

By | April 1, 2017

Through similar mechanisms, amino acid depletion in culture and cytokine activity in the tumor microenvironment prompt cancer cells to metastasize.

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image: Circadian Rhythms Influence Treatment Effects

Circadian Rhythms Influence Treatment Effects

By | April 1, 2017

Across many diseases, taking medication at specific times of day may make the therapy more effective.

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image: Infographic: Circadian Clock Affects Health and Disease

Infographic: Circadian Clock Affects Health and Disease

By | April 1, 2017

The body's rhythms could affect numerous ailments as well as how people respond to treatments.

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image: Infographic: Mechanisms of Resistance

Infographic: Mechanisms of Resistance

By | April 1, 2017

Cancers appear to be able to evolve resistance to many of the therapies doctors have tried.

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image: House Votes to Limit EPA Decision Making

House Votes to Limit EPA Decision Making

By | March 31, 2017

The “HONEST” Act, passed by the House this week, would restrict the nature of the research that can inform new regulations at the Environmental Protection Agency. Meanwhile, EPA Administrator Scott Pruitt overrules the agency’s previous recommendation on chlorpyrifos. 

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Researchers in the country speak out as a second version of Canada’s national budget retains freezes spending at key science funding councils.

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