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image: Location, Location, Location

Location, Location, Location

By | April 1, 2017

Since first proposing that a cell’s function and biology depend on its surroundings, Mina Bissell continues to probe the role of the extracellular matrix.

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image: Making CAR T-Cell Therapy Safer

Making CAR T-Cell Therapy Safer

By | April 1, 2017

Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.

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image: Notable Science Quotes

Notable Science Quotes

By | April 1, 2017

Eugene Garfield, the cancer moonshot, employee genetic testing, and more

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Measuring PD-L1 levels was a great start. Now we need to quantify more protein biomarkers, assess the tumor mutational landscape, and examine immune cell signatures, too.

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image: Circadian Rhythms Influence Treatment Effects

Circadian Rhythms Influence Treatment Effects

By | April 1, 2017

Across many diseases, taking medication at specific times of day may make the therapy more effective.

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image: Infographic: Circadian Clock Affects Health and Disease

Infographic: Circadian Clock Affects Health and Disease

By | April 1, 2017

The body's rhythms could affect numerous ailments as well as how people respond to treatments.

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image: House Votes to Limit EPA Decision Making

House Votes to Limit EPA Decision Making

By | March 31, 2017

The “HONEST” Act, passed by the House this week, would restrict the nature of the research that can inform new regulations at the Environmental Protection Agency. Meanwhile, EPA Administrator Scott Pruitt overrules the agency’s previous recommendation on chlorpyrifos. 

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Researchers in the country speak out as a second version of Canada’s national budget retains freezes spending at key science funding councils.

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image: Should Healthy People Have Their Exomes Sequenced?

Should Healthy People Have Their Exomes Sequenced?

By | March 24, 2017

With its announced launch of a whole-exome sequencing service for apparently healthy individuals, Ambry Genetics is the latest company to enter this growing market. But whether these services are useful for most people remains up for debate.  

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image: Pathway to Polio Virulence Revealed

Pathway to Polio Virulence Revealed

By | March 23, 2017

Using epidemiological and laboratory data, scientists have mapped out a sequence of mutations through which the attenuated oral polio vaccine reverts to a virulent virus.

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