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tag autism spectrum disorder cell molecular biology developmental biology
Researchers CHOOSE Organoids to Investigate Neurodevelopment
Deanna MacNeil, PhD
| Jan 29, 2024
| 4 min read
A 3D variation of pooled CRISPR screens could connect the dots between autism spectrum disorder genetics and cell fate pathways in the developing brain.
Molecular Hub of Autism?
Jef Akst
| Dec 30, 2014
| 2 min read
Researchers identify a network that includes many genes previously linked to autism spectrum disorders.
Top 7 in developmental biology
Bob Grant
| Dec 17, 2010
| 3 min read
A snapshot of the most highly ranked articles in developmental biology, from Faculty of 1000
Immune Role in Brain Disorder?
Hannah Waters
| Mar 19, 2012
| 3 min read
Replacing immune cells in a mouse model of Rett syndrome, a developmental brain disorder, improved symptoms, suggesting a new target for treatment.
Mini Brains Model Autism
Ruth Williams
| Jul 16, 2015
| 3 min read
Patient-derived organoids reveal autism spectrum disorder–associated anomalies.
Opinion: New Models for ASDs
Alysson R. Muotri
| May 13, 2015
| 3 min read
The study of mini “brains” in a dish, derived from patient cells, offers a novel approach for autism spectrum disorder research.
Exploring the Past, Present, and Future of Brain Organoids
Niki Spahich, PhD
| Feb 18, 2024
| 5 min read
Paola Arlotta seeks to understand the complex symphony of brain development in vitro by using organoid models.
Different Forms of Autism Have Opposite Problems with Brain Precursor Cells
Charles Choi
| Jun 13, 2022
| 3 min read
Compared with cells taken from non-autistic controls, neural precursors from autistic boys proliferated in atypical ways, a small study finds.
Mutations in Autism-Linked Gene Cause Membrane Mischief
Holly Barker, PhD,
Spectrum
| Jan 26, 2023
| 4 min read
Inactivating TAOK1 prompts tentacle-like protrusions to form all over a neuron’s surface, revealing the gene’s role in molding the membrane.
Immunity-Linked Genes Expressed Differently in Brains of Autistic People
Laura Dattaro,
Spectrum
| Jan 11, 2023
| 4 min read
Data from postmortem brain tissues adds to the evidence that inflammation is associated with autism.
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