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Guts and Glory
Anna Azvolinsky | Apr 1, 2016 | 9 min read
An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
Notebook
The Scientist Staff | Dec 7, 1997 | 7 min read
November was a rollercoaster month at the National Academy of Sciences (NAS). First, the United States Supreme Court declined to hear NASA's appeal of a lower court ruling subjecting the academy and its committees to the Federal Advisory Committees Act (FACA) of 1972. Animal rights groups argued that under FACA there should have been more public representation on a committee set up to revise the NIH Guide for the Care and Use of Laboratory Animals (R. Finn, The Scientist, July 22, 1996, page 1)
Ready, Reset, Go
Karen Hopkin | Mar 1, 2011 | 9 min read
By Karen Hopkin Ready, Reset, Go Rudolf Jaenisch enjoys climbing mountains, rafting rapids, and unraveling the secrets of pluripotency—knowledge that could someday lead to personalized regenerative medicine. RUDOLF JAENISCH Professor of Biology, MIT Member, Whitehead Institute F1000 Head of Faculty, Genomics & Genetics Porter Gifford It was a misbehaving virus that drew Rudolf Jaenisch to epigenetics. As a postdoc in Arnold Levine’s
2020 Top 10 Innovations
The Scientist | Dec 1, 2020 | 10+ min read
From a rapid molecular test for COVID-19 to tools that can characterize the antibodies produced in the plasma of patients recovering from the disease, this year’s winners reflect the research community’s shared focus in a challenging year.
Ready, Reset, Go
Karen Hopkin | Mar 1, 2011 | 9 min read
Rudolf Jaenisch enjoys climbing mountains, rafting rapids, and unraveling the secrets of pluripotency—knowledge that could someday lead to personalized regenerative medicine.
Master of the Cell
Judy Lieberman | Apr 1, 2010 | 10+ min read
By Judy Lieberman Master of the Cell RNA interference, with its powerful promise of therapy for many diseases, may also act as a master regulator of most—if not all—cellular processes. RNA silencing. Computer artwork showing a length of RNA (yellow with red rings) bound to an RNA-induced silencing complex (RISC). © Medi-Mation Ltd / Photo Researchers, Inc. ne of the biggest surprises in biology in the past d
On the Fast Track in Functional Proteomics
A. J. S. Rayl | Apr 1, 2001 | 8 min read
Graphic: Leza Berardone Researchers in Canada and Denmark are employing mass spectrometry, three-dimensional tissue biology, and supercomputing to blaze a trail in functional proteomics research. In the process, they're putting their company, MDS Proteomics Inc., on the fast track in the latest race to develop new drug targets and eventually better treatments for all kinds of diseases. By using this combination of technologies, MDS Proteomics is accelerating the process of identifying, analyzin
Cloning Capsized?
Ted Agres | Aug 19, 2001 | 10+ min read
Biopharmaceutical researchers fear how pending federal legislation outlawing the cloning of human cells will restrict their abilities to find cures for major degenerative diseases.1,2 Some also see lawmakers impinging on established nonhuman cloning techniques essential for the discovery of new drugs and therapies. The source of all this worry? The US House of Representatives passed July 31 by a wide margin a bill (H.R. 2505) sponsored by Reps. David Weldon (R-Fla.) and Bart Stupak (D-Mich.) th
A Question of Chimeras
Clare Kittredge(ckittredge@the-scientist.com) | Apr 10, 2005 | 6 min read
Looking to cure a host of neurodegenerative diseases, StemCells, a Palo Alto, Calif.-based company, has transplanted human neural stem cells into the brains of thousands of mice.

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