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SP140, an epigenetic reader protein mutated in a number of autoimmune disorders, is essential for macrophage function and preventing intestinal inflammation, scientists show. 

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image: Study: Most Long Noncoding RNAs Likely Functional

Study: Most Long Noncoding RNAs Likely Functional

By | March 2, 2017

Nearly 20,000 lncRNAs identified in human cells may play some role in cellular activities.

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image: Human Gut Microbe Transplant Alters Mouse Behavior

Human Gut Microbe Transplant Alters Mouse Behavior

By | March 1, 2017

Fecal transplants from humans with irritable bowel syndrome and anxiety into mice lead to similar symptoms and anxiety-like behavior in the rodents, researchers report.  

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image: A Selection of CRISPR Proof-of-Principle Studies

A Selection of CRISPR Proof-of-Principle Studies

By | March 1, 2017

Advice on how to deploy the latest techniques in your own lab

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image: Massively Parallel Perturbations

Massively Parallel Perturbations

By | March 1, 2017

Scientists combine CRISPR gene editing with single-cell sequencing for genotype-phenotype screens.

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image: Infographic: Single-Cell CRISPR Screens

Infographic: Single-Cell CRISPR Screens

By | March 1, 2017

See how two new methods track responses to unique genetic manipulations in numerous individual cells in parallel.

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image: How Bacteria Interfere with Insect Reproduction

How Bacteria Interfere with Insect Reproduction

By | February 28, 2017

Scientists identify the genes responsible for bacteria-controlled sterility in arthropods.

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image: Smallest Cas9 Ortholog Reported

Smallest Cas9 Ortholog Reported

By | February 23, 2017

Researchers demonstrate the delivery of AAV-packaged CRISPR-CjCas9 into the muscles and eyes of mice.

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image: An Aging-Related Effect on the Circadian Clock

An Aging-Related Effect on the Circadian Clock

By | February 21, 2017

Stress-related genes may be preferentially and rhythmically expressed as part of the circadian rhythms of older fruit flies, researchers report.  

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image: Hybrid Mammoth Embryo Coming Soon?

Hybrid Mammoth Embryo Coming Soon?

By | February 21, 2017

Harvard geneticist George Church says that he will likely be able to create a hybrid wooly mammoth-elephant embryo in the near future.

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