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tag memory formation genetics genomics immunology

3D Rendering of Molecular Interaction in CAR Chimeric Antigen Receptor
Next-generation CAR and TCR Cancer Therapies
Danielle Gerhard, PhD | Mar 15, 2024 | 10+ min read
From smart receptors to novel biologics, scientists plan to overcome the challenges of treating solid tumors.
One Protein to Rule Them All
Shelby Bradford, PhD | Feb 28, 2024 | 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Top 7 in Immunology
Edyta Zielinska | Aug 2, 2011 | 3 min read
A snapshot of the most highly ranked articles in microbiology and related areas, from Faculty of 1000
A Look at Drosophila Pattern Formation
Jeffrey Perkel | Sep 2, 2001 | 9 min read
Researchers interested in gene expression studies adopt one of two approaches. They can either examine the expression of a given gene in a population of cells in aggregate, or they can study the gene on a cell-by-cell basis in situ. The advantage of the former approach is its simplicity: It is generally easy to prepare RNA or protein from a given tissue sample and to probe it for the gene or protein of interest. But there are several disadvantages associated with the population approach. First o
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
Eat Yourself to Live: Autophagy’s Role in Health and Disease
Vikramjit Lahiri and Daniel J. Klionsky | Mar 1, 2018 | 10+ min read
New details of the molecular process by which our cells consume themselves point to therapeutic potential.
Nonradioactive Probes Protect Scientists And Environment
Holly Ahern | Apr 29, 1990 | 5 min read
For many years, geneticists determined the genetic makeup of organisms by examining the physical characteristics of their offspring. But with the discovery of the structure of the DNA double helix, first published by James D. Watson and Francis H.C. Crick in 1953 (Nature, 171:964-7), the science of genetics was forever changed. Scientists soon developed techniques to study the genetic message found in all living cells at the molecular level. One of most important of these methods was the use of
2020 Top 10 Innovations
The Scientist | Dec 1, 2020 | 10+ min read
From a rapid molecular test for COVID-19 to tools that can characterize the antibodies produced in the plasma of patients recovering from the disease, this year’s winners reflect the research community’s shared focus in a challenging year.
Downsizing DNA Assays
Kelli Miller | Jan 6, 2002 | 2 min read
Detection of the DNA sequences responsible for genetically transmitted diseases can open doors to a potential cure, but the research can be expensive and tedious. Princeton, N.J. -based PharmaSeq's light-powered, reusable transponders could provide an inexpensive alternative for performing DNA assays. A nanotransponder measuring just 250 x 250 x 100 µm (less than 1/1000th the size of a grain of rice) is the newest DNA microchip in PharmaSeq's family of microtransponders. Competitive devic

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