Kate Travis | Jan 1, 2007 | 9 min read
Deciphering Immunology's Dirty Secret Can innate immune adjuvants save vaccinology? By Kate Travis ARTICLE EXTRAS 1 Why, he wondered, did scientists have to include bits of bacteria or aluminum hydroxide with a vaccine to get an immune response? Janeway hypothesized and later proved that so-called pattern recognition receptors identify invading pathogens and trigger an immediate reaction against the i