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tag gene patents culture ecology cell molecular biology

A close up of a tick held in a pair of forceps, with Kevin Esvelt’s face out of focus in the background.
CRISPR Gene Drives and the Future of Evolution
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Genetic engineering pioneer Kevin Esvelt’s work highlights biotechnology’s immense potential for good—but also for catastrophe.
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
A person moving the hands of a vintage clock backwards.
Synthetic Circuits Reveal the Key to Rewinding the Cellular Clock
Charlene Lancaster, PhD | Mar 12, 2024 | 4 min read
Using a circuit-based system, scientists determined the ideal transcription factor levels to promote the successful reprogramming of fibroblasts into induced pluripotent stem cells.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
A mutated cell with a spiky membrane
Mutations in Autism-Linked Gene Cause Membrane Mischief
Holly Barker, PhD, Spectrum | Jan 26, 2023 | 4 min read
Inactivating TAOK1 prompts tentacle-like protrusions to form all over a neuron’s surface, revealing the gene’s role in molding the membrane.
Postmodern Culture: Maximizing Cell Culture Output At Every Level
Grant Meisenholder | Jul 4, 1999 | 10 min read
Date: July 5, 1999Products for High-Volume Tissue Culture The Automation Partnership's CELLMATETM Automated Cell Culture Processing System Mammalian cell culture has finally come into its own as a way to produce cells, proteins, or sub-cellular components in large scale. Recent advances in cell culture systems are allowing scientists to better circumvent problems associated with bacterial systems such as incomplete protein expression, toxin contamination, and incompatibility. Today's wide arra
Fluorophore Fingerprinting; Gene Therapy Hybrid; Low-Level Annotation
Ivan Oransky | Jul 27, 2003 | 4 min read
PATENT WATCH | Fluorophore Fingerprinting The Molecular Sciences Institute in Berkeley, Calif., has been awarded a patent for a protein fingerprint system (US patent 6,569,685, issued May 27, 2003). The patent covers a method that, in the simplest case, consists of covalently modifying reactive residues using orthogonal chemistries, by attaching one fluorophore to lysine residues under appropriate chemical conditions, and a different fluorophore to cysteine residues. "The general idea is to
Image of an abstract fractal blue and green sea shell.
Cell Chirality Offers Clues to the Mystery of Body Asymmetry
Catherine Offord | Feb 1, 2022 | 10+ min read
Researchers explore the idea that molecular patterns in individual cells could underlie the development of a left and a right in animals.
Top 7 papers in cell biology
Jef Akst | Dec 5, 2010 | 3 min read
Just in time for ASCB -- see the cell biology articles most highly ranked by F1000

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