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A mouse study reveals a causal link between changes in intestinal microbiota and increasing inflammation as the rodents age.

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Mice exposed to low doses of penicillin in utero or as young pups exhibited long-term behavioral differences not seen in their non-exposed counterparts, according to a study.

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Recolonizing middle-aged animals with bacteria from younger ones kept killifish alive longer than usual, researchers report.

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image: Book Excerpt from <em>The Politics of Cancer</em>

Book Excerpt from The Politics of Cancer

By | April 1, 2017

In Chapter 2, “Identifying the Culprits,” author Wendy Whitman Cobb describes how small-government, anti-regulation conservatism can hinder the fight against cancer.

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image: Contributors

Contributors

By | April 1, 2017

Meet some of the people featured in the April 2017 issue of The Scientist.

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image: Hitting It Out of the Park

Hitting It Out of the Park

By | April 1, 2017

Cancer can be as evasive and slippery as a spitball, but new immunotherapies are starting to connect.

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image: How Will Cancer Research Fare Under Trump?

How Will Cancer Research Fare Under Trump?

By | April 1, 2017

The new administration has not yet made its intentions clear.

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image: Location, Location, Location

Location, Location, Location

By | April 1, 2017

Since first proposing that a cell’s function and biology depend on its surroundings, Mina Bissell continues to probe the role of the extracellular matrix.

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image: Making CAR T-Cell Therapy Safer

Making CAR T-Cell Therapy Safer

By | April 1, 2017

Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.

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Measuring PD-L1 levels was a great start. Now we need to quantify more protein biomarkers, assess the tumor mutational landscape, and examine immune cell signatures, too.

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