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image: Short, Strong Signals

Short, Strong Signals

By | March 25, 2015

Methylation increases both the activity and instability of the signaling protein Notch.


image: Irisin Skepticism Goes Way Back

Irisin Skepticism Goes Way Back

By | March 18, 2015

Post-publication peer reviewers had questioned data about the supposed fat-browning enzyme from the get-go.

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image: The 2015 Salary Survey Is Complete

The 2015 Salary Survey Is Complete

By | March 13, 2015

Thanks to everyone who participated in this year's survey. Please check back in November for the results.


image: Book Excerpt from <em>Galileo’s Middle Finger</em>

Book Excerpt from Galileo’s Middle Finger

By | March 10, 2015

In Chapter 4, “A Show-Me State of Mind,” author Alice Dreger describes the start of her journey studying scientists who had conducted controversial research.

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image: <em>Apiarium</em>, 1625

Apiarium, 1625

By | March 1, 2015

Galileo’s improvements to the microscope led to the first published observations using such an instrument.


image: Growth Hormone Guidance

Growth Hormone Guidance

By | March 1, 2015

Intact growth hormone signaling pathways are needed for methionine restriction to extend mouse lifespan.


image: Is Anatomy Destiny?

Is Anatomy Destiny?

By | March 1, 2015

Alice Dreger, historian of science and author of this month's "Reading Frames," explores the blurry lines between male and female in her 2010 TED talk.

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image: Long Live Collagen

Long Live Collagen

By | March 1, 2015

Increased collagen expression is a common feature of many different pathways to extended longevity in worms.


image: Speaking of Science

Speaking of Science

By | March 1, 2015

March 2015's selection of notable quotes


image: Stirring the Pot

Stirring the Pot

By | March 1, 2015

How to navigate the slings and arrows of conducting “controversial” research



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