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image: Making CAR T-Cell Therapy Safer

Making CAR T-Cell Therapy Safer

By | April 1, 2017

Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.

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image: Notable Science Quotes

Notable Science Quotes

By | April 1, 2017

Eugene Garfield, the cancer moonshot, employee genetic testing, and more

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Measuring PD-L1 levels was a great start. Now we need to quantify more protein biomarkers, assess the tumor mutational landscape, and examine immune cell signatures, too.

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image: How Cancers Evolve Drug Resistance

How Cancers Evolve Drug Resistance

By | April 1, 2017

Researchers unravel the sophisticated ways cancers evade treatments, including immunotherapies, designed to destroy them.

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image: Neoantigens Enable Personalized Cancer Immunotherapy

Neoantigens Enable Personalized Cancer Immunotherapy

By | April 1, 2017

Tumors’ mutations can encode the seeds of their own destruction, in the form of immunogenic peptides recognized by T cells.

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While studying the progression of healthy cells into cancerous ones, researchers discover a way to engraft human blood cells into animals.

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image: Starvation Response Triggers Melanoma Invasion

Starvation Response Triggers Melanoma Invasion

By | April 1, 2017

Through similar mechanisms, amino acid depletion in culture and cytokine activity in the tumor microenvironment prompt cancer cells to metastasize.

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image: Infographic: Antibody Cancer Therapy

Infographic: Antibody Cancer Therapy

By | April 1, 2017

An experimental technique removes T cells that aid in vitro tumor growth.

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image: Infographic: Inside Melanoma Invasion

Infographic: Inside Melanoma Invasion

By | April 1, 2017

See what cytokine activity and cellular starvation have to do with cancer metastasis.

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image: Infographic: Mechanisms of Resistance

Infographic: Mechanisms of Resistance

By | April 1, 2017

Cancers appear to be able to evolve resistance to many of the therapies doctors have tried.

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