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image: One Receptor, Two Ligands, Different Responses

One Receptor, Two Ligands, Different Responses

By | August 31, 2016

Host and bacterial ligands that interact with the same cell-surface receptor induce different activities in human macrophages. 

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The marsupials’ genomes show evidence of a rapid evolutionary response to selection imposed by devil facial tumor disease.

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image: One Antigen Receptor Induces Two T cell Types

One Antigen Receptor Induces Two T cell Types

By | August 26, 2016

Precursor T cells bearing the same antigen receptor adopt two different fates in mice.

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image: Stem Cells Drive Cancer Risk in Mice

Stem Cells Drive Cancer Risk in Mice

By | August 26, 2016

Mutations that arise during stem cell division contribute to the development of cancers in a variety of organs, according to a study.

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image: Seven More Retractions for Cancer Researcher

Seven More Retractions for Cancer Researcher

By | August 10, 2016

All of the papers had been published in the Journal of Biological Chemistry.

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image: Macrophages Respond to Liver Injury

Macrophages Respond to Liver Injury

By | August 1, 2016

In mice, immune cells from the body cavity surrounding organs arrive at the site of damage to chew up the nuclei of dead cells.

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image: Newly Discovered Emergency Responders to Liver Damage

Newly Discovered Emergency Responders to Liver Damage

By | August 1, 2016

Immune cells called macrophages from the peritoneal cavity of mice migrate to injured livers and aid in repair.

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image: CRISPR Therapy to Enter Trials

CRISPR Therapy to Enter Trials

By | July 25, 2016

Researchers in China will use the CRISPR-Cas9 system to edit T cells extracted from patients with cancer before those cells are returned to the body to target malignant ones.

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image: Arming Synthetic Bacteria Against Cancer

Arming Synthetic Bacteria Against Cancer

By | July 20, 2016

Researchers engineer bacteria that deliver an anti-tumor toxin in mice before self-destructing. 

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image: Distinguishing Circulating Tumor from Normal Cell-Free DNA

Distinguishing Circulating Tumor from Normal Cell-Free DNA

By | July 19, 2016

Fragments of circulating DNA from tumors are around 20 to 30 base pairs shorter than those from healthy cells, researchers report.

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