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image: What it Takes to Develop Better Drugs for Kids

What it Takes to Develop Better Drugs for Kids

By | March 1, 2012

Over the past 15 years, new laws and regulations in the United States and the European Union have expanded to require the inclusion of pediatric patients in clinical drug trials.  

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image: David Sabatini: Demystifying mTOR

David Sabatini: Demystifying mTOR

By | March 1, 2012

Principal Investigator, Whitehead Institute for Biomedical Research. Associate Professor, Department of Biology, Massachusetts Institute of Technology. Age: 44

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image: Delivering Silence

Delivering Silence

By | March 1, 2012

Using RNA viruses to silence genes could optimize tissue targeting while reducing toxicity.

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image: How Drugs Interact with a Baby’s Parts

How Drugs Interact with a Baby’s Parts

By | March 1, 2012

A lot changes in a child’s body over the course of development, and not all changes occur linearly: gene expression can fluctuate, and organs can perform different functions on the way to their final purpose in the body. Here are some of the key deve

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image: Suspected Effects of Vitamin D

Suspected Effects of Vitamin D

By | March 1, 2012

Vitamin D has a variety of actions in the body. It binds to the vitamin D receptor (VDR), which then binds to the retinoid X receptor (RXR) and activates the expression of numerous genes. 

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image: Biota Babble

Biota Babble

By | March 1, 2012

Editor's choice in immunology

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image: Child-Proofing Drugs

Child-Proofing Drugs

By | March 1, 2012

When children need medications, getting the dosing and method of administration right is like trying to hit a moving target with an untried weapon.

6 Comments

image: Combing the Cancer Genome

Combing the Cancer Genome

By | March 1, 2012

A guided tour through the main online resources for analyzing cancer genomics data

5 Comments

image: Vitamin D on Trial

Vitamin D on Trial

By | March 1, 2012

Prevention trials for vitamins and supplements are notoriously difficult, but some researchers aren’t giving up on finding proof that vitamin D helps ward off disease.

52 Comments

image: Skin-Deep Immunity

Skin-Deep Immunity

By | February 29, 2012

Immune cells in skin provide powerful protection against infection, suggesting new routes for vaccination.

6 Comments

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