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Mouse organoids reveal that a protein active during embryonic development joins forces with gene enhancers to revert cancer cells to an earlier developmental state.

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Two freely available databases include data on hundreds of human cancer cell lines. 

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image: Stem Cells Seek Out Tumors Based on Stiffness

Stem Cells Seek Out Tumors Based on Stiffness

By | July 26, 2017

The technique, demonstrated in mice using engineered mesenchymal stem cells, has potential for both diagnosis and treatment.

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image: Dogs with Duchenne Treated with Gene Therapy

Dogs with Duchenne Treated with Gene Therapy

By | July 25, 2017

Researchers restored muscle function in animals with muscular dystrophy.

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A new method stimulates B cells to make human antigen-specific antibodies, obviating the need for vaccinating blood donors or hunting for rare B cells.

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image: Immunized Cows Produce Anti-HIV Antibodies

Immunized Cows Produce Anti-HIV Antibodies

By | July 20, 2017

Cows injected with a protein that mimics HIV’s envelope make broadly neutralizing antibodies that inhibit multiple strains of the virus.

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image: DNA Origami

DNA Origami

By | July 17, 2017

Will complex, folded synthetic DNA molecules one day serve as capsules to deliver drugs to cancer cells?

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Using single-cell RNA sequencing, scientists characterize new populations of dendritic cells and monocytes.

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The presence of similar light-emitting enzymes in the distantly related organisms lends new insight into bioluminescence evolution.

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image: Uncovering Functions of Circular RNAs

Uncovering Functions of Circular RNAs

By | July 17, 2017

Recent research has revealed many surprises about circular RNAs, from findings that they are translated in vivo to links between their expression and disease.

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