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The Scientist

» cancer, developmental biology and immunology

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image: Mouse Made For You

Mouse Made For You

By | March 23, 2012

Mice “avatars” grafted with patient tumor tissue help identify effective drug regimens.

4 Comments

image: Let Them Eat Dirt

Let Them Eat Dirt

By | March 22, 2012

Early exposure to microbes shapes the mammalian immune system by subduing inflammatory T cells.

30 Comments

image: Immune Role in Brain Disorder?

Immune Role in Brain Disorder?

By | March 19, 2012

Replacing immune cells in a mouse model of Rett syndrome, a developmental brain disorder, improved symptoms, suggesting a new target for treatment.

2 Comments

image: High Tumor Heterogeneity Confirmed

High Tumor Heterogeneity Confirmed

By | March 9, 2012

One biopsy may not provide enough information about the array of mutations in cancer to devise treatments based on a tumor’s genetic profile.

2 Comments

image: Transplant Without Drugs?

Transplant Without Drugs?

By | March 8, 2012

A new method for transplanting immunologically mismatched organs may remove the need for life-long immunosuppressive drugs to prevent rejection.

6 Comments

image: Genome Digest

Genome Digest

By | March 7, 2012

Meet the species whose DNA has recently been sequenced.

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image: Designer Aspirin Fights Cancer

Designer Aspirin Fights Cancer

By | March 5, 2012

Early experiments show that a hybrid form of the common pain reliever can effectively inhibit the growth of many tumor types.

0 Comments

image: What it Takes to Develop Better Drugs for Kids

What it Takes to Develop Better Drugs for Kids

By | March 1, 2012

Over the past 15 years, new laws and regulations in the United States and the European Union have expanded to require the inclusion of pediatric patients in clinical drug trials.  

2 Comments

image: David Sabatini: Demystifying mTOR

David Sabatini: Demystifying mTOR

By | March 1, 2012

Principal Investigator, Whitehead Institute for Biomedical Research. Associate Professor, Department of Biology, Massachusetts Institute of Technology. Age: 44

0 Comments

image: Delivering Silence

Delivering Silence

By | March 1, 2012

Using RNA viruses to silence genes could optimize tissue targeting while reducing toxicity.

0 Comments

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