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The Scientist

» cancer, developmental biology and immunology

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image: Neutralizing HIV

Neutralizing HIV

By | June 18, 2015

Engineered immunogens based on conserved patches of the virus’s envelope protein point to new strategies for vaccine design.

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image: Sperm From Ovaries

Sperm From Ovaries

By | June 11, 2015

With the deletion of a single gene, female Japanese rice fish can produce sperm. 

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image: More Lab-Made Nucleotides

More Lab-Made Nucleotides

By | June 8, 2015

Artificial bases that act like the real deal can be designed to bind specifically to tumor cells.

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image: NCI Gets Personal

NCI Gets Personal

By | June 2, 2015

The National Cancer Institute is launching a Phase 2 trial matching patients with specific mutations to drugs tailored to those genetic changes.

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image: Brain Drain

Brain Drain

By | June 1, 2015

The brain contains lymphatic vessels similar to those found elsewhere in the body, a mouse study shows.

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image: New Immunity

New Immunity

By | June 1, 2015

A scaffolding protein forms the hub of a newly identified immune pathway in plants.

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image: Viral Immunotherapy for Melanoma

Viral Immunotherapy for Melanoma

By | May 28, 2015

Phase 3 data from a clinical trial show a positive response to a melanoma treatment based on a modified herpesvirus.

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image: Cancer-Driving Mutations Common in Normal Skin Cells

Cancer-Driving Mutations Common in Normal Skin Cells

By | May 21, 2015

A deep-sequencing analysis reveals that non-malignant skin cells harbor many more cancer-driving mutations than previously expected. 

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image: Targeting Protein Domains with CRISPR

Targeting Protein Domains with CRISPR

By | May 13, 2015

Researchers use the genome-editing tool to mutate binding pockets and identify potential anti-cancer drug targets.

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image: Dino Snouts from Chicken Beaks

Dino Snouts from Chicken Beaks

By | May 13, 2015

Researchers tweak gene expression in chicken embryos that may have been crucial to the evolutionary transition from dinosaur noses to bird bills.

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