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image: Disease-Causing Mutations in Healthy People

Disease-Causing Mutations in Healthy People

By | June 8, 2015

A large-scale genome sequencing effort identifies mutations with disease-causing potential at higher rates than expected.

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image: More Lab-Made Nucleotides

More Lab-Made Nucleotides

By | June 8, 2015

Artificial bases that act like the real deal can be designed to bind specifically to tumor cells.

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image: Mosaic Mutations May Not Be Rare

Mosaic Mutations May Not Be Rare

By | June 5, 2015

Somatic mosaicism may be responsible for a larger proportion of genomic variability within humans than previously thought.

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image: The Roots of Schizophrenia

The Roots of Schizophrenia

By | June 4, 2015

Researchers link disease-associated mutations to excitatory and inhibitory signaling in the brain.

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image: NCI Gets Personal

NCI Gets Personal

By | June 2, 2015

The National Cancer Institute is launching a Phase 2 trial matching patients with specific mutations to drugs tailored to those genetic changes.

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image: New Legs to Stand On

New Legs to Stand On

By | June 1, 2015

Reconstructing the past using ancient DNA

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image: Not So Noncoding

Not So Noncoding

By | June 1, 2015

An RNA thought to be noncoding in fact encodes a small protein that regulates calcium uptake in muscle.

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image: Silencing Surprise

Silencing Surprise

By | June 1, 2015

A chromatin remodeler in embryonic stem cells clears the DNA for mRNA transcription while stifling the expression of noncoding transcripts.

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image: Genomes Point the Way

Genomes Point the Way

By | May 28, 2015

Sequence analysis of Egyptian, Ethiopian, and non-African peoples indicates a likely route taken by modern humans migrating out of Africa.

1 Comment

image: Viral Immunotherapy for Melanoma

Viral Immunotherapy for Melanoma

By | May 28, 2015

Phase 3 data from a clinical trial show a positive response to a melanoma treatment based on a modified herpesvirus.

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