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Cancer Sequencing Controls

By | April 15, 2015

Comparing a patient’s tumor DNA sequence with that of her normal tissue can improve researchers’ identification of disease-associated mutations.

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image: Clam Cancer Rips Along Atlantic Coast

Clam Cancer Rips Along Atlantic Coast

By | April 9, 2015

A leukemia that’s killing far-flung populations of softshell clams may be contagious. 

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image: Insulin Interference Triggers Cancer-Linked Cachexia

Insulin Interference Triggers Cancer-Linked Cachexia

By | April 6, 2015

A tumor-secreted protein interferes with insulin signaling to cause cancer-linked muscle wasting in fruit flies. 

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Personalized Cancer Vaccines

By | April 2, 2015

A dendritic cell vaccine targeting melanoma patients’ tumor-specific mutations can activate a broad range of cancer-fighting T cells. 

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image: Book Excerpt from <em>p53</em>

Book Excerpt from p53

By | April 1, 2015

In Chapter 12, "Of Mice and Men," author Sue Armstrong recounts the point at which researchers moved from working with p53 in tissue culture to studying the gene in animal models.

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Bursting Cancer’s Bubble

By | April 1, 2015

Scientists make oxygen-filled microbubbles designed to increase tumor sensitivity to radiation.

3 Comments

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Cancer Immunotherapist

By | April 1, 2015

Scientist to Watch Yvonne Saenger explains recent advances in using biomarkers to identify cancer patients who might benefit most from immunotherapy.

1 Comment

image: Cancer Kismet

Cancer Kismet

By | April 1, 2015

Fate mapping allows researchers to follow cancer progression from its cell type of origin.

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Contributors

By | April 1, 2015

Meet some of the people featured in the April 2015 issue of The Scientist.

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image: Control ALT, Delete Cancer

Control ALT, Delete Cancer

By , , and | April 1, 2015

Treating cancer by shutting down the alternative lengthening of telomeres (ALT) pathway

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