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» cancer and developmental biology

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image: Short, Strong Signals

Short, Strong Signals

By | March 25, 2015

Methylation increases both the activity and instability of the signaling protein Notch.

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image: Speaking of Science

Speaking of Science

By | March 1, 2015

March 2015's selection of notable quotes

3 Comments

image: Engineered Biomarkers Could ID Cancer Cells

Engineered Biomarkers Could ID Cancer Cells

By | February 23, 2015

Scientists develop synthetic blood-based biomarkers to amplify tumor signals in a mouse model.

2 Comments

image: Exploring the Epigenome

Exploring the Epigenome

By | February 18, 2015

A National Institutes of Health-funded consortium publishes 111 reference maps of DNA and histone marks.

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image: Culturing Changes Cells

Culturing Changes Cells

By | February 3, 2015

Within days of their transfer to a dish, a certain epigenetic mark vanishes from mouse cells.

2 Comments

image: Benefits of Missing MYC

Benefits of Missing MYC

By | January 22, 2015

Mice engineered to have just one copy of the gene Myc live longer, healthier lives than wild-type animals.

1 Comment

image: Roche Snags Tumor Tester for $1B

Roche Snags Tumor Tester for $1B

By | January 13, 2015

The pharmaceutical company bought a majority stake in Foundation Medicine, a firm that develops personalized cancer-medicine diagnostics.

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image: Stem Cell Divisions Help Explain Cancer Risk

Stem Cell Divisions Help Explain Cancer Risk

By | January 1, 2015

An analysis of 31 tissues finds that random mutations acquired during stem cell divisions correlate with lifetime cancer risk—more so than heritable mutations and environmental factors combined.  

7 Comments

image: Fertility Treatment Fallout

Fertility Treatment Fallout

By | January 1, 2015

Mouse offspring conceived by in vitro fertilization are metabolically different from naturally conceived mice.

8 Comments

image: Focus on Sex

Focus on Sex

By | December 29, 2014

In 2014, new research findings and guidelines brought increased attention to biological differences between males and females.

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