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The Scientist

» cancer and developmental biology

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image: NCI Gets Personal

NCI Gets Personal

By | June 2, 2015

The National Cancer Institute is launching a Phase 2 trial matching patients with specific mutations to drugs tailored to those genetic changes.

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image: Viral Immunotherapy for Melanoma

Viral Immunotherapy for Melanoma

By | May 28, 2015

Phase 3 data from a clinical trial show a positive response to a melanoma treatment based on a modified herpesvirus.

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image: Cancer-Driving Mutations Common in Normal Skin Cells

Cancer-Driving Mutations Common in Normal Skin Cells

By | May 21, 2015

A deep-sequencing analysis reveals that non-malignant skin cells harbor many more cancer-driving mutations than previously expected. 

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image: Targeting Protein Domains with CRISPR

Targeting Protein Domains with CRISPR

By | May 13, 2015

Researchers use the genome-editing tool to mutate binding pockets and identify potential anti-cancer drug targets.

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image: Dino Snouts from Chicken Beaks

Dino Snouts from Chicken Beaks

By | May 13, 2015

Researchers tweak gene expression in chicken embryos that may have been crucial to the evolutionary transition from dinosaur noses to bird bills.

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image: Organoid Biobank

Organoid Biobank

By | May 11, 2015

From the tissue of numerous colon cancer patients, researchers build 3-D cultures of tumors.

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image: Prominent Cell Biologist Dies

Prominent Cell Biologist Dies

By | May 4, 2015

Cytoskeleton specialist Alan Hall was best known for unpacking the roles of Rho GTPases.   

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image: <em>The Scientist</em> on the Pulse, April 23

The Scientist on the Pulse, April 23

By | April 23, 2015

Hot topics in cancer research from the annual meeting of the American Association for Cancer Research

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image: The Lasting Effects of Obesity

The Lasting Effects of Obesity

By | April 23, 2015

Losing weight does not mitigate the effects of obesity on tumor development in mice.

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image: Personalized Devices Predict Cancer Drug Response

Personalized Devices Predict Cancer Drug Response

By | April 22, 2015

Two teams have developed tumor-implantable drug delivery devices to study real-time responses to multiple therapies in cancer patients.

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