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image: Novartis Drops Gene Therapy Research

Novartis Drops Gene Therapy Research

By | September 6, 2016

The company has shuttered its experimental cell and gene cancer therapy unit, firing more than 100 researchers.

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image: Week in Review: August 29–September 2

Week in Review: August 29–September 2

By | September 2, 2016

Roger Tsien dies; the CRISPR patent dispute you’ve never heard of; immunotherapy for Alzheimer’s; Tasmanian devils developing resistance to transmissible cancer

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image: Designing In Vitro Models of the Blood-Brain Barrier

Designing In Vitro Models of the Blood-Brain Barrier

By | September 1, 2016

Choosing the right model, be it 3-D or 2-D, requires wading through varied cell sources, cell types, and cell culture conditions.

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image: The Challenges of Rare-Disease Research

The Challenges of Rare-Disease Research

By | September 1, 2016

With few resources and hesitant investors, basic scientists must rely on clinicians, patient advocates, and their own keen eye for biological connections.

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image: Popular Tumor Cell Line Contaminated

Popular Tumor Cell Line Contaminated

By | August 31, 2016

A commercially available glioblastoma cell line appears to be from a different source than its stated origins.

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image: One Receptor, Two Ligands, Different Responses

One Receptor, Two Ligands, Different Responses

By | August 31, 2016

Host and bacterial ligands that interact with the same cell-surface receptor induce different activities in human macrophages. 

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The marsupials’ genomes show evidence of a rapid evolutionary response to selection imposed by devil facial tumor disease.

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image: One Antigen Receptor Induces Two T cell Types

One Antigen Receptor Induces Two T cell Types

By | August 26, 2016

Precursor T cells bearing the same antigen receptor adopt two different fates in mice.

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image: Stem Cells Drive Cancer Risk in Mice

Stem Cells Drive Cancer Risk in Mice

By | August 26, 2016

Mutations that arise during stem cell division contribute to the development of cancers in a variety of organs, according to a study.

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Disrupting the light/dark cycles of pregnant mice, researchers observe detrimental effects in the mouths of the animals’ pups.

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