ADVERTISEMENT
ADVERTISEMENT

cancer, genetics & genomics

Screening with CRISPR
Kelly Rae Chi | Jun 1, 2016 | 7 min read
Ever-improving CRISPR-based tools are already ripe for large-scale genetic screens.
AACR Q&A: Angelika Amon
The Scientist | Apr 19, 2016 | 3 min read
The aneuploidy expert shares what she has learned at the American Association for Cancer Research annual meeting.
A Tree Takes Root
Ashley P. Taylor | Apr 1, 2016 | 4 min read
Four apparently unrelated individuals share a common ancestor from whom they inherited a rare mutation that predisposed them to the cancer they share.
Pulling It All Together
Kate Yandell | Apr 1, 2016 | 9 min read
Systems-biology approaches offer new strategies for finding hard-to-identify drug targets for cancer.
Death in the Dust
The Scientist | Mar 31, 2016 | 1 min read
Follow Michele Carbone as he tracks down the genetic and environmental drivers of mesothelioma and other cancers.
Mutations Not Tied to Metastasis
Kerry Grens | Feb 25, 2016 | 3 min read
Clinical cases link immune changes to a cancer’s spread through the body, but find no role for so-called “driver” mutations.
Managing Methylation
Karen Zusi | Jan 1, 2016 | 2 min read
A long noncoding RNA associated with DNA methylation has the power to regulate colon cancer growth in vitro.
Telomerase Overdrive
Ashley P. Taylor | Jan 1, 2016 | 2 min read
Two mutations in a gene involved in telomere extension reverse the gene’s epigenetic silencing.
Direct-to-Consumer Liquid Biopsy
Kerry Grens | Sep 13, 2015 | 2 min read
Some doctors advise shoppers to be skeptical of a newly marketed cancer diagnostic.
Toward Blood-based Cancer Detection
Jyoti Madhusoodanan | Jul 7, 2015 | 4 min read
Circulating tumor cells, exosomes, and DNA can improve the diagnosis of many cancers. But are liquid biopsies ready for prime time?
Time Bungles Precision Medicine
Kerry Grens | Apr 20, 2015 | 2 min read
Personalized pancreatic cancer therapies based on tumor genomics may take too long to prepare to be helpful, according to a small clinical trial.
Cancer Sequencing Controls
Ruth Williams | Apr 15, 2015 | 3 min read
Comparing a patient’s tumor DNA sequence with that of her normal tissue can improve researchers’ identification of disease-associated mutations.
Clam Cancer Rips Along Atlantic Coast
Jyoti Madhusoodanan | Apr 9, 2015 | 3 min read
A leukemia that’s killing far-flung populations of softshell clams may be contagious. 
Setbacks and Great Leaps
Sue Armstrong | Apr 1, 2015 | 3 min read
The tale of p53, a widely studied tumor suppressor gene, illustrates the inventiveness of researchers who turn mishaps into discoveries.
The Challenges of Precision
Adam Marcus | Apr 1, 2015 | 3 min read
Researchers face roadblocks to treating an individual patient’s cancer as a unique disease.
Cancer Kismet
Jenny Rood | Apr 1, 2015 | 4 min read
Fate mapping allows researchers to follow cancer progression from its cell type of origin.
Two-Faced RNAs
Kerry Grens | Apr 1, 2015 | 4 min read
The same microRNAs can have opposing roles in cancer.
To Each His Own
Mary Beth Aberlin | Apr 1, 2015 | 3 min read
Cancer treatment becomes more and more personal.
Contributors
Jenny Rood | Apr 1, 2015 | 3 min read
Meet some of the people featured in the April 2015 issue of The Scientist.
Resisting Cancer
George Klein | Apr 1, 2015 | 9 min read
If one out of three people develops cancer, that means two others don’t. Understanding why could lead to insights relevant to prevention and treatment.
ADVERTISEMENT