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cancer, genetics & genomics

Week in Review: September 23–27
Tracy Vence | Sep 27, 2013 | 4 min read
Antibiotic cycling makes a comeback in the lab; how life scientists can learn from astronauts; napping to conquer fears; deconstructing the cancer R&D crisis
Different Cancers, Same Mutations
Ruth Williams | Sep 26, 2013 | 3 min read
Scientists document common genetic alterations in cancers of different origins.
Capsule Reviews
Bob Grant | Sep 1, 2013 | 3 min read
Rocket Girl, The Cancer Chronicles, Abominable Science!, and The Sports Gene
Week in Review: August 12–16
Tracy Vence | Aug 16, 2013 | 3 min read
Engineered immune cells attack tumors; a mouth microbe that can cause cancer; HIV may heighten cocaine’s high; craving high-fat foods
Mutation Patterns Underlie Cancers
Kerry Grens | Aug 15, 2013 | 2 min read
More than 20 genome-wide mutational “signatures” account for the vast majority of 30 common cancers.
Mouth Microbe Turns Carcinogenic
Tracy Vence | Aug 14, 2013 | 3 min read
Two studies peg down how a bacterium indigenous to the oral cavity can contribute to the development of colorectal cancer.
Week in Review: August 5–9
Jef Akst | Aug 9, 2013 | 5 min read
Flu researchers propose H7N9 studies; NIH makes deal to share HeLa genome; herbal “remedies” can cause cancer; scientists record grid cell activity in humans
Cancer-Causing Herbal Remedies
Ruth Williams | Aug 7, 2013 | 3 min read
A potent carcinogen lurks within certain traditional Chinese medicines.
Bacterial DNA in Human Genomes
Ed Yong | Jun 20, 2013 | 4 min read
A new study finds strong evidence that bacteria can transfer genes into human genomes, especially in cancer cells.
Identifying Spurious Cancer Mutations
Dan Cossins | Jun 19, 2013 | 2 min read
Researchers reveal why analyses of cancer-causing mutations are riddled with false positives and demonstrate a new approach that eliminates the problem.
Week in Review: April 8-12
Jef Akst | Apr 12, 2013 | 3 min read
Hot topics from the AACR meeting; the ongoing debate about pesticides’ effects on bees; a treasure trove of baby dinos; conservation on social media
Up, Up, and Array
Megan Scudellari | Apr 1, 2013 | 8 min read
By scrutinizing gene expression profiles instead of individual oncogenes, Todd Golub launched a powerful platform for diagnosing, classifying, and treating cancer.
Cancer Clinical Trials of Tomorrow
Tomasz M. Beer | Apr 1, 2013 | 4 min read
Advances in genomics and cancer biology will alter the design of human cancer studies.
Making Cancer More Transparent
Mary Beth Aberlin | Apr 1, 2013 | 3 min read
A decade into the age of genomics, science is generating a flood of data that will help in the quest to eradicate the disease.
Cancer Gene Bonanza
Ed Yong | Mar 27, 2013 | 3 min read
International collaboration doubles the number of genetic regions associated with breast, prostate, and ovarian cancers.
Architecture Reveals Genome’s Secrets
Sabrina Richards | Nov 25, 2012 | 4 min read
Three-dimensional genome maps are leading to a deeper understanding of how the genome’s form influences its function.
Court Rules Gene Patents Valid
Cristina Luiggi | Aug 17, 2012 | 1 min read
Myriad Genetics can hold patents on the BRAC1 and BRAC2 oncogenes, but not on tests comparing DNA sequences.
DNA, Contortionist
Kerry Grens | Aug 1, 2012 | 2 min read
The DNA forms known as G-quadruplexes are finally discovered in human cells.
Modeling the Cell
Jef Akst | Jul 23, 2012 | 2 min read
The first full computer model of a single-celled organism mimics the bacterium’s behaviors and paves the way to more complete disease models.
Jumping Genes a Cause of Cancer?
Ruth Williams | Jun 28, 2012 | 3 min read
Genome sequence analysis confirms mobile genetic elements are a mutagenic mechanism in a variety of cancers.
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