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Mouse organoids reveal that a protein active during embryonic development joins forces with gene enhancers to revert cancer cells to an earlier developmental state.

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Two freely available databases include data on hundreds of human cancer cell lines. 

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image: Stem Cells Seek Out Tumors Based on Stiffness

Stem Cells Seek Out Tumors Based on Stiffness

By | July 26, 2017

The technique, demonstrated in mice using engineered mesenchymal stem cells, has potential for both diagnosis and treatment.

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The bacteria also promoted the growth of human colon cancer cells in a dish.

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image: FDA Votes Yes on CAR T-Cell Therapy

FDA Votes Yes on CAR T-Cell Therapy

By | July 13, 2017

A Food and Drug Administration advisory panel unanimously calls for agency approval of the cell therapy for the treatment of resistant leukemia. 

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image: Cell Cannibalism as Cancer Defense

Cell Cannibalism as Cancer Defense

By | July 11, 2017

A new study suggests that the mysterious process by which one cell consumes another may be triggered by cell division, potentially helping to fight tumor growth.

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Researchers overestimate the reliability of findings from animal studies that are part of the Reproducibility Project: Cancer Biology.

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image: Transgenic Mouse Illuminates Melanoma Metastasis

Transgenic Mouse Illuminates Melanoma Metastasis

By | June 28, 2017

Glowing cells mark the routes of tumor spread by way of newly formed lymph vessels. 

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image: Cancer Studies Seem Replicable

Cancer Studies Seem Replicable

By | June 27, 2017

In the latest findings from the Reproducibility Project: Cancer Biology, independent researchers achieve results that mirror those of two earlier papers.

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An analysis of human cancer genome projects uncovers a counterintuitive loss of ribosomal gene copies.

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