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cancer

Mitochondrial DNA Plays a Role in Metastasis
Kerry Grens | Apr 18, 2018 | 2 min read
Experiments in mice show that mitochondria, both within the tumor and beyond, can make the difference between promoting or inhibiting cancer spread.
How Kidney Cancer Evolves
Jim Daley | Apr 18, 2018 | 2 min read
Renal cell carcinoma tumors have three different evolutionary fates, each associated with specific clinical outcomes.
Immune Therapy Improves Lung Cancer Patients’ Survival
Jim Daley | Apr 16, 2018 | 2 min read
Pembrolizumab combined with chemotherapy nearly doubles survival rates and shrinks tumors in some individuals.
Antibody Combo Expands Response to Checkpoint Inhibitor in Mice
Kerry Grens | Apr 16, 2018 | 2 min read
Genetic analyses uncover cellular hallmarks of bladder cancer tumors that don’t respond, but interfering with one of those characteristics in a mouse model causes tumors to shrink.  
Birth Defects Linked to Increased Risk of Childhood Cancer
Jim Daley | Apr 15, 2018 | 2 min read
Certain non-chromosomal defects are strongly associated with specific childhood cancers.
Wound-Healing in Mice Triggers Growth of Dormant Tumors
Jim Daley | Apr 12, 2018 | 2 min read
Treating mice with anti-inflammatory drugs following surgery reduced the size of tumors.
Image of the Day: Tumor Organoids
The Scientist and The Scientist Staff | Apr 11, 2018 | 1 min read
Miniature versions of bladder cancers could help physicians identify personalized treatment options for patients.
Human Cancer Drugs May Be Effective in Tasmanian Devils
Shawna Williams | Apr 9, 2018 | 2 min read
A new study reveals similarities between the transmissible cancers that infect the endangered marsupials, and hints at ways to treat them.
Hundreds of Inherited Gene Variants Contribute to Cancer
Abby Olena, PhD | Apr 5, 2018 | 3 min read
In the largest study of its kind to date, researchers find more than 850 rare, heritable genetic alterations that can predispose humans to cancer.
OSU Professor Falsified Data on Eight Papers, Resigns
Catherine Offord | Apr 2, 2018 | 2 min read
Ching-Shih Chen’s research involved anticancer therapeutics that were being tested in clinical trials.
A Radical Intervention, 1894
Catherine Offord | Apr 1, 2018 | 3 min read
William Halsted’s approach to mastectomy took the medical world by storm at the turn of the last century.
A Neuroscientist’s Journey Through Madness
Barbara Lipska with Elaine McArdle | Apr 1, 2018 | 3 min read
After I was diagnosed with brain cancer and started to lose my mental health, the importance of my job came into clear focus.
PARP Inhibitors Are Improving the Outlook of Hard-to-Treat Cancers
Vicki Brower | Apr 1, 2018 | 9 min read
With three recent FDA approvals, and a number of Phase 3 trials ongoing, the drugs are seeing a surge in interest.
Of Mice and Metastasis
Amanda B. Keener | Apr 1, 2018 | 7 min read
Tools for studying how cancer spreads
Ilana Chefetz Confronts Ovarian Cancer
Jim Daley | Apr 1, 2018 | 3 min read
The University of Minnesota researcher is on the front lines in the fight against the disease.
Caught on Camera
The Scientist | Apr 1, 2018 | 2 min read
Selected Images of the Day from the-scientist.com
Cancer Evolutionist: A Profile of Charles Swanton
Anna Azvolinsky | Apr 1, 2018 | 9 min read
Motivated by his father’s cancer diagnosis, the Francis Crick Institute cancer geneticist has been revealing the ways tumors evolve and why they are so difficult to treat.
Mutant RAS Proteins Team Up for Oncogenicity
Jim Daley | Apr 1, 2018 | 2 min read
Mice with cancer whose KRAS proteins couldn’t link together had much better survival outcomes than those whose oncogenic mutant paired with wild-type KRAS.
Boosting Immunotherapy Treatments in Mouse Colon Cancer
Jim Daley | Apr 1, 2018 | 2 min read
Mice treated with an immunostimulant had better outcomes when researchers blocked the expression of TNFR2, a compound that helps tumors evade immune attack.
Chromosomal Instability Drives Cancer Metastasis
Jim Daley | Apr 1, 2018 | 2 min read
In the presence of cytosolic DNA, cancer cells activate antiviral pathways that disguise them as immune cells.
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