A new report outlines ways in which omics-based technologies can be shuttled more safely and effectively from the bench to the clinic.
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Mice “avatars” grafted with patient tumor tissue help identify effective drug regimens.
One biopsy may not provide enough information about the array of mutations in cancer to devise treatments based on a tumor’s genetic profile.
Early experiments show that a hybrid form of the common pain reliever can effectively inhibit the growth of many tumor types.
Over the past 15 years, new laws and regulations in the United States and the European Union have expanded to require the inclusion of pediatric patients in clinical drug trials. Before these laws were enacted, the US Food and Drug Administration (F
Principal Investigator, Whitehead Institute for Biomedical Research. Associate Professor, Department of Biology, Massachusetts Institute of Technology. Age: 44
Using RNA viruses to silence genes could optimize tissue targeting while reducing toxicity.
Vitamin D has a variety of actions in the body. It binds to the vitamin D receptor (VDR), which then binds to the retinoid X receptor (RXR) and activates the expression of numerous genes. Through this mechanism, vitamin D promotes calcium absorption
A guided tour through the main online resources for analyzing cancer genomics data
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