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tag genome disease medicine neuroscience evolution

Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
Can Viruses in the Genome Cause Disease?
Katarina Zimmer | Jan 1, 2019 | 10+ min read
Clinical trials that target human endogenous retroviruses to treat multiple sclerosis, ALS, and other ailments are underway, but many questions remain about how these sequences may disrupt our biology.
Aging-Related Diseases May Be a Negative Outcome of Human Evolution
Sukanya Charuchandra | May 31, 2018 | 3 min read
Genetic adaptations for human brain development also make us vulnerable to Alzheimer’s disease, according to a new study.  
Conceptual image showing molecules making up a brain shape
The Noncoding Regulators of the Brain
Christie Wilcox, PhD | Sep 12, 2022 | 10+ min read
Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Illustration showing a puzzle piece of DNA being removed
Large Scientific Collaborations Aim to Complete Human Genome
Brianna Chrisman and Jordan Eizenga | Sep 1, 2022 | 10+ min read
Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.
A Nile rat sitting atop fruits
Genome Spotlight: Nile Rat (Avicanthis niloticus)
Christie Wilcox, PhD | Nov 23, 2022 | 4 min read
A reference sequence for this emerging model organism will facilitate research on type 2 diabetes and the health effects of circadian rhythm disruption.
march 2019 the scientist profile
Master Decoder: A Profile of Kári Stefánsson
Anna Azvolinsky | Mar 1, 2019 | 9 min read
A neurologist by training, Stefánsson founded Iceland-based deCODE Genetics to explore what the human genome can tell us about disease and our species’ evolution.
The Devolution of Evolution
Leonid Moroz | Nov 1, 2010 | 4 min read
By Leonid Moroz The Devolution of Evolution Why evolution and biosystematics courses must be included in all biomedical curricula. Nearly 40 years ago Theodosius Dobzhansky wrote: “Nothing in biology makes sense except in the light of evolution.” How is it, then, that so few newly minted PhDs in the biological sciences have taken any formal graduate school courses in evolution or biodiversity? This fosters a knowledge gap that can become difficult t

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