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tag cancer cell lines evolution culture

Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
One Protein to Rule Them All
Shelby Bradford, PhD | Feb 28, 2024 | 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
Cell Lines Gain Cancer-Related Mutations
Kerry Grens | Apr 27, 2017 | 1 min read
A screen of human embryonic stem cell lines finds several that accumulated changes in the gene TP53, including aberrations commonly seen in cancer.
Artist’s rendition of a blue-green DNA double helix, viewed lengthwise from within one end.
Stem Cell Lines Riddled With Undetected Mutations
Dan Robitzski | Aug 12, 2022 | 4 min read
Most of the human induced pluripotent stem cells stored at major cell line repositories and used in research harbor thousands of DNA errors, a study finds, highlighting the need for improved quality control measures.
Defined Primary Cell Culture and Media
The Scientist Creative Services Team in collaboration with MilliporeSigma | Jul 29, 2021 | 3 min read
A new partnership opens the door for a source of highly purified human primary cells and defined cell culture media.
Cancer Researchers Use Evolution to Target Drug Resistance
Catherine Offord | Apr 1, 2020 | 10+ min read
New therapeutic approaches in oncology aim to manipulate or block cancer’s adaptation to treatment.
Non-Chromosomal DNA Drives Tumor Evolution
Anna Azvolinsky | Feb 8, 2017 | 4 min read
Researchers discover that short pieces of DNA harboring oncogenes are relatively widespread in cancer.
3d rendered medically accurate illustration of a human embryo anatomy
The Ephemeral Life of the Placenta
Danielle Gerhard, PhD | Dec 4, 2023 | 10+ min read
Recent advances in modeling the human placenta, the least understood organ, may inform placental disorders like preeclampsia.
A Y-shaped pink, blue, and light green antibody is in focus on a background of blurred pink and purple color, with other antibodies out of focus in the background.
Phage Display: Finding the One in a Million
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
A combinatorial approach enabled high-throughput screening of protein libraries for desired target binding.
Composite image showing genes radiating from tumor cells
Jumping Genes’ Role in Cancer
Diana Kwon | Mar 1, 2023 | 8 min read
Transposons may be key players in how tumors develop and spread, but they also keep cancer at bay in some circumstances.

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