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tag transcriptional regulation microbiology culture evolution

bacteria inside a biofilm
How Bacterial Communities Divvy up Duties
Holly Barker, PhD | Jun 1, 2023 | 10+ min read
Biofilms are home to millions of microbes, but disrupting their interactions could produce more effective antibiotics.
Updated Sept 1
coronavirus pandemic news articles covid-19 sars-cov-2 virology research science
Follow the Coronavirus Outbreak
The Scientist | Feb 20, 2020 | 10+ min read
Saliva tests screen staff and students at University of Illinois; Study ranks species most susceptible to SARS-CoV-2 infection; COVID-19 clinical trials test drugs that inhibit kinin system
A Bacterial Messenger Molecule Extends Healthspan
Sandhya Sekar | Aug 27, 2017 | 3 min read
E. coli that make indoles protect older worms, flies, and mice from frailty. 
Mining Bacterial Small Molecules
L. Caetano M. Antunes, Julian E. Davies and B. Brett Finlay | Jan 1, 2011 | 10 min read
As much as rainforests or deep-sea vents, the human gut holds rich stores of microbial chemicals that should be mined for their pharmacological potential.
Unlikely Heroes
Nicole Johnston | Jun 1, 2003 | 6 min read
Dr. R. Thomas Broker Among model organisms, bacteria hold a unique place, as both models of infection and pathogenesis, and as research tools. More to the point, molecular biology was built upon the cell walls of lowly bacteria: The processes of DNA replication, RNA transcription, and protein translation, not to mention gene regulation, were all worked out in bacteria. Those early studies provided the foundations to understanding the more complex processes in eukaryotes. Despite their relati
Sharing the Bounty
Michelle G. Rooks and Wendy S. Garrett | Aug 1, 2011 | 10+ min read
Gut bacteria may be the missing piece that explains the connection between diet and cancer risk.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
The Language of Bacteria ... and Just About Everything Else
Kendra Rumbaugh | Sep 12, 2004 | 5 min read
FIGURE 1:Courtesy of Kendra RumbaughEukaryotic and prokaryotic signaling molecules have similar functions. Mammalian steroid hormones bind to cognate nuclear hormone receptors; Pseudomonas aeruginosa autoinducer N-3-oxododecanoyl homoserine lactone acts as a ligand for the transcriptional activator LasR and is essential for cell-to-cell communication resulting in biofilm formation.Mammals possess sophisticated endocrine networks in which hormonal signals modulate hundreds of biological effects s
translation gene genetics ribosome enhancers knowable magazine
What Does It Look Like to “Turn On” a Gene?
Alla Katsnelson, Casey Rentz, and Knowable Magazine | May 3, 2019 | 8 min read
Only recently have scientists directly witnessed this most pivotal of events in biology, thanks to new technology that allows them to observe the process in living cells. It’s teaching them a lot.
Surpassing the Law of Averages
Jeffrey M. Perkel | Sep 1, 2009 | 7 min read
By Jeffrey M. Perkel Surpassing the Law of Averages How to expose the behaviors of genes, RNA, proteins, and metabolites in single cells. By necessity or convenience, almost everything we know about biochemistry and molecular biology derives from bulk behavior: From gene regulation to Michaelis-Menten kinetics, we understand biology in terms of what the “average” cell in a population does. But, as Jonathan Weissman of the University of Califo

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