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» transcriptional regulation and immunology

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image: Enhancer and Promoter Atlases

Enhancer and Promoter Atlases

By | March 26, 2014

Consortium annotates the human genome with cell type-specific information about transcription start sites, active enhancers, and their expression throughout the body.

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image: DNA Bends Control Gene Activation

DNA Bends Control Gene Activation

By | March 25, 2014

Genomic structures called i-motifs signal DNA activation, while hairpin loops signal gene suppression.  

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image: Vitamin A’s Influence on Immunity

Vitamin A’s Influence on Immunity

By | March 19, 2014

Exposure to vitamin A in the womb influences immune system development and lifelong ability to fight infections, a mouse study shows. 

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image: DNA Damage Scout

DNA Damage Scout

By | February 11, 2014

Researchers are beginning to appreciate a role for RNA polymerase beyond gene transcription.

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image: Week in Review: February 3–7

Week in Review: February 3–7

By | February 7, 2014

Federal stem cell regulations vary; Salmonella exploit host immune system; microglia help maintain synaptic connections; prosthesis re-creates feeling of touch

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image: Immune Response Promotes Infection

Immune Response Promotes Infection

By | February 6, 2014

Salmonella enterica can exploit a standard immune response in mice to promote its own growth.

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image: Pruning Synapses Improves Brain Connections

Pruning Synapses Improves Brain Connections

By | February 2, 2014

Without microglia to pluck off unwanted synapses in early life, mouse brains develop with weaker connections, leading to altered social behavior.

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image: Polymer Protects Mouse Heart

Polymer Protects Mouse Heart

By | January 20, 2014

Injection of microscopic particles of a plastic-like material protects mice from cardiac tissue damage following heart attack.

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image: Daytime Sleep Alters Human Transcriptome

Daytime Sleep Alters Human Transcriptome

By | January 20, 2014

A mistimed sleep cycle drastically reduces the number of genes that are expressed in a 24-hour rhythm.

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image: How HIV Destroys Immune Cells

How HIV Destroys Immune Cells

By | December 19, 2013

During HIV infection, CD4 T cells in lymphoid tissues initiate a highly inflammatory form of cell death that helps cripple the immune system.  

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