Steven Benowitz | Apr 14, 1996 | 3 min read
X.D. Wang, R. Sato, M.S. Brown, X.X. Hua, J.L. Goldstein, "Srebp-1, a membrane-bound transcription factor released by sterol-regulated proteolysis," Cell, 77:53-62, 1994. (Cited in more than 65 publications as of February 1996) Comments by Joseph L. Goldstein, University of Texas Southwestern Medical Center SURPRISED: Joseph Goldstein investigates cholesterol control. The work reported in this paper reveals the mechanism for transcriptional control of the genes that regulate cholesterol in